ALEXIS Biochemicals: µ-Conotoxin GS

ALX-630-047

Revised 10-Oct-08

µ-Conotoxin GS
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Neurotoxins

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-630-047-C500		500 µg	790.00 USD

Product Specification

SEQUENCE:	H-Ala-Cys-Ser-Gly-Arg-Gly-Ser-Arg-Cys-Hyp-Hyp-Gln-Cys-Cys-Met-Gly-Leu-Arg-Cys-Gly-Arg-Gly-Asn-Pro-Gln-Lys-Cys-Ile-Gly-Ala-His-Gla-Asp-Val-OH (Disulfide bonds between Cys²-Cys¹⁴, Cys⁹-Cys¹⁹and Cys¹³-Cys²⁷) (Gla = L-γ-Carboxyglutamic acid)
FORMULA:	C₁₃₉H₂₂₀N₅₂O₄₈S₇
MW:	3612.1
SOURCE/HOST:	Synthetic. Originally isolated from Conus geographus.
QUANTITY:	0.55mg (0.15µmol)
CONCENTRATION:	0.1mM after reconstitution.
PURITY:	≥97%
APPEARANCE:	Lyophilized.
RECONSTITUTION:	Do not remove the cap. Inject 1.5ml of water or 0.9% sodium chloride into the vial using a syring. Let the contents dissolve thoroughly.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 1 year when stored at -20°C. Stock solutions are stable for a few weeks at -20°C.
HANDLING:	After reconstitution, prepare aliquots and store at -20°C.
HAZARD:	POTENT NEUROTOXIN.

Product Description

Neurotoxin. Na⁺channel blocker. Not for sale in U.S.A.

Product Specific Literature References

A novel sodium channel inhibitor from Conus geographus: purification, structure, and pharmacological properties: Y. Yanagawa, et al.; Biochemistry 27, 6256 (1988) Abstract
Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry: J.M. Hill, et al.; Structure 5, 571 (1997) Abstract
Using the deadly mu-conotoxins as probes of voltage-gated sodium channels: R. A. Li & G. F. Tomaselli; Toxicon 44, 117 (2004), (Review) Abstract

Further Categories Containing This Product:

Na+ Channels • Peptides

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