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ALX-550-013 Revised 07-May-03
1-Aminocyclobutane-cis-1,3-dicarboxylic acid
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SYNONYMS cis-ACBD
cis-2,4-Methanoglutamic acid
PRODUCT LINE Neurobiology
PRODUCT CATEGORY NMDA Receptors/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-550-013-M005   5 mg 65.00 USD Add To Cart
Product Specification
FORMULA: C6H9NO4
MW: 159.1
CAS NUMBER: 117488-23-0
APPEARANCE: White solid.
SOLUBILITY: Soluble in dilute aqueous base.
HANDLING: Protect from light.

Product Description
Very potent and selective NMDA receptor agonist.
Product Specific Literature References
Cis-2,4-methanoglutamate is a potent and selective N-methyl-D-aspartate receptor agonist: T.H. Lanthorn, et al.; Eur. J. Pharmacol. 182, 397 (1990) Abstract
Synthesis and activity of a potent N-methyl-D-aspartic acid agonist, trans-1-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acids: R.D. Allan, et al.; J. Med. Chem. 33, 2905 (1990) Abstract
Inhibition of high affinity L-glutamic acid uptake into rat cortical synaptosomes by the conformationally restricted analogue of glutamic acid, cis-1-aminocyclobutane-1,3-dicarboxylic acid: E.J. Fletcher, et al.; Neurosci. Lett. 121, 133 (1991) Abstract
 
 

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