ALEXIS Biochemicals: 12(S)-HpETE

ALX-340-057

Revised 10-Jul-08

12(S)-HpETE
SYNONYMS	12-(S)-Hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid
PRODUCT LINE	Inflammation
PRODUCT CATEGORY	Eicosanoids Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-340-057-C025		25 µg	162.00 USD
ALX-340-057-C050		50 µg	308.00 USD

Product Specification

FORMULA:	C₂₀H₃₂O₄
MW:	336.5
CAS NUMBER:	71774-10-2
PURITY:	≥98%
FORMULATION:	Liquid. Solution in ethanol.
SOLUBILITY:	Soluble in DMSO or dimethyl formamide; slightly soluble in PBS, pH 7.2 (0.8mg/ml) or 0.1M Na₂CO₃ (2mg/ml).
SHIPPING:	SHIPPED ON DRY ICE
LONG TERM STORAGE:	-80°C
USE/STABILITY:	Stable for at least 6 months after receipt when stored at -80°C. Product is highly unstable in aqueous solution. We recommend using aqueous solutions within fifteen minutes.

Product Description

Endogenous TRPV1 agonist (K_i=0.35µM).

Product Specific Literature References

Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances: S.W. Hwang, et al.; PNAS 97, 6155 (2000) Abstract
Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia: J. Shin, et al.; PNAS 99, 10150 (2002) Abstract

General Information

BACKGROUND/TECHNICAL INFORMATION

To change the solvent, evaporate the ethanol under a gentle stream of nitrogen and immediately add the solvent of choice.

Further Categories Containing This Product:

Fos & Jun Proteins / Related Products • Endovanilloids

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