ALEXIS Biochemicals: 2-Amino-4-methylpyridine

ALX-270-449

Revised 20-Mar-07

2-Amino-4-methylpyridine
SYNONYMS	2-Amino-4-picoline
PRODUCT LINE	Nitric Oxide Pathway
PRODUCT CATEGORY	NOS Inhibitors (NOS Induction & Enzyme Activity)

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-449-G001		1 g	20.00 USD

Product Specification

FORMULA:	C₆H₈N₂
MW:	108.1
CAS NUMBER:	695-34-1
MERCK INDEX:	14: 466
RTECS:	TJ5150000
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in 100% ethanol, methanol, dimethylformamide or water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for 3 years after receipt when stored at -20°C.
HAZARD:	TOXIC.

Product Description

Potent inhibitor of inducible nitric oxide synthase (iNOS; NOS II) both in vitro and in vivo. Analgesic agent.

Product Specific Literature References

2-Amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo: W.S. Faraci, et al.; Br. J. Pharmacol. 119, 1101 (1996) Abstract
Analgesic activity of 2-amino-4-methylpyridine, a novel NO synthase inhibitor: E.R. Pettipher, et al.; Inflamm. Res. 46 Suppl 2, S135 (1997) Abstract
Inhibition of nitric oxide synthase aggravates cisplatin-induced nephrotoxicity: effect of 2-amino-4-methylpyridine: S.Y. Saad, et al.; Chemotherapy 48, 309 (2002) Abstract

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