ALEXIS Biochemicals: 2,3-Di-O-butyryl-D-myo-inositol 1,4,5,6-tetrakisphosphate octakis(propionoxymethyl)ester

ALX-307-060

Revised 28-Nov-08

2,3-Di-O-butyryl-D-myo-inositol 1,4,5,6-tetrakisphosphate octakis(propionoxymethyl)ester
SYNONYMS	Bt₂Ins(1,4,5,6)P₄/PM
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Inositols & Inositolphosphates / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-307-060-1		1 Vial	320.00 USD

Product Specification

FORMULA:	C₄₆H₇₆O₃₆P₄
MW:	1329.0
QUANTITY:	1µmol
PURITY:	≥98% (HPLC)
APPEARANCE:	Clear syrup.
SOLUBILITY:	Soluble in toluol and DMSO.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Do not freeze mixtures of Pluronic®, DMSO and inositolphosphates!
HANDLING:	Protect from moisture.
IDENTITY:	Identity determined by ¹H-NMR, ³¹P-NMR and MS.

Product Description

Cell permeable derivative of Prod. No. ALX-307-034.

Product Specific Literature References

D-myo-Inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to Salmonella invasion inhibits phosphoinositide 3-kinase signaling pathways: L. Eckmann, et al.; PNAS 94, 14456 (1997) Abstract; Full Text
Enzyme-assisted total synthesis of the optical antipodes D-myo-inositol 3,4,5-trisphosphate and D-myo-inositol 1,5, 6-trisphosphate: aspects of their structure-activity relationship to biologically active inositol phosphates: S. Adelt, et al.; J. Med. Chem. 42, 1262 (1999) Abstract; Full Text

General Information

BACKGROUND/TECHNICAL INFORMATION

Includes 1 vial of 10% Pluronic^® (F127) solution in DMSO.

Recommendations on application (Cuvette Experiments)
- Prepare a 100mM stock solution by adding 20µl of DMSO to 1µmol of inositol product.
- In a fresh vial mix 1µl of the stock solution and 2µl of Pluronic^® as supplied.
- Add 500µl of your cell suspension and mix carefully.
- Add this mixture to the remaining cell suspension (~500µl) and mix carefully.
Note: Cell suspension should not contain more than 1% of DMSO.

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