ALEXIS Biochemicals: 2,5-Di-t-butylhydroquinone

ALX-270-093

Revised 03-Feb-05

2,5-Di-t-butylhydroquinone
SYNONYMS	DBHQ
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Ca2+-ATPase / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-093-G001		1 g	16.00 USD

Product Specification

FORMULA:	C₁₄H₂₂O₂
MW:	222.3
CAS NUMBER:	88-58-4
PURITY:	≥99%
APPEARANCE:	Off-white powder.
SOLUBILITY:	Soluble in DMSO or 100% ethanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+20°C

Product Description

SERCA pump inhibitor. Induces the release of Ca²⁺from agonist-sensitive and agonist-insensitive intracellular stores without increasing IP₃levels. Inhibitor of liver microsomal calcium ion sequestration.

Product Specific Literature References

2,5-Di(tert-butyl)-1,4-benzohydroquinone--a novel inhibitor of liver microsomal Ca2+ sequestration: G.A. Moore, et al.; FEBS Lett. 224, 331 (1987) Abstract
2,5-Di-(tert-butyl)-1,4-benzohydroquinone rapidly elevates cytosolic Ca2+ concentration by mobilizing the inositol 1,4,5-trisphosphate- sensitive Ca2+ pool: G.E. Kass, et al.; J. Biol. Chem. 264, 15192 (1989) Abstract; Full Text
Agonist-sensitive and -insensitive intracellular Ca2+ pools. Separate Ca(2+)-releasing mechanisms revealed by manoalide and benzohydroquinone: S. Muallem, et al.; Biochem. J. 279, 367 (1991) Abstract
Cyclopiazonic acid depletes intracellular Ca2+ stores and activates an influx pathway for divalent cations in HL-60 cells: N. Demaurex, et al.; J. Biol. Chem. 267, 2318 (1992) Abstract; Full Text

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