ALEXIS Biochemicals: 2,5,6-Tri-O-butyryl-D-myo-inositol 1,3,4-trisphosphate hexakis(acetoxymethyl)ester

ALX-307-045

Revised 29-Mar-07

2,5,6-Tri-O-butyryl-D-myo-inositol 1,3,4-trisphosphate hexakis(acetoxymethyl)ester
SYNONYMS	Bt₃Ins(1,3,4)P₃/AM
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Inositols & Inositolphosphates / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-307-045-1		1 Vial	320.00 USD

Product Specification

FORMULA:	C₃₆H₅₇O₃₀P₃
MW:	1062.8
QUANTITY:	1µmol
PURITY:	≥98% (HPLC)
APPEARANCE:	Clear syrup.
SOLUBILITY:	Soluble in toluene or DMSO.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Do not freeze mixtures of Pluronic^®, DMSO and inositolphosphates!
HANDLING:	Protect from moisture.
IDENTITY:	Identity determined by ¹H-NMR, ³¹P-NMR and MS.

Product Description

Cell permeable derivative of Prod. No. ALX-307-006.

Product Specific Literature References

A membrane-permeant, bioactivatable derivative of Ins(1,3,4)P3 and its effect on Cl(-)-secretion from T84 cells: M.T. Rudolf, et al.; Bioorg. Med. Chem. Lett. 8, 1857 (1998) Abstract
Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate: X. Yang, et al.; J. Biol. Chem. 274, 18973 (1999) Abstract; Full Text

General Information

BACKGROUND/TECHNICAL INFORMATION

Includes 1 vial of 10% Pluronic^® (F127) solution in DMSO.

Recommendations on application (Cuvette Experiments)
- Prepare a 100mM stock solution by adding 10µl of DMSO to 1µmol of inositol product.
- In a fresh vial mix 1µl of the stock solution and 2µl of Pluronic^® as supplied.
- Add 500µl of your cell suspension and mix carefully.
- Add this mixture to the remaining cell suspension (~500µl) and mix carefully.
Note: Cell suspension should not contain more than 1% of DMSO.

MANUFACTURER

Manufactured by SiChem, Germany

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