ALEXIS Biochemicals: (2S)-α-Ethylglutamic acid

ALX-550-324

Revised 28-Jan-05

(2S)-α-Ethylglutamic acid
SYNONYMS	EGLU
PRODUCT LINE	Neurobiology
PRODUCT CATEGORY	Glutamate Receptors (Metabotropic) / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-550-324-M001		1 mg	35.00 USD
ALX-550-324-M005		5 mg	95.00 USD

Product Specification

FORMULA:	C₇H₁₃NO₄
MW:	175.2
PURITY:	≥98%
APPEARANCE:	White solid.
SOLUBILITY:	Soluble in dilute aqueous base.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C

Product Description

Group II mGluR antagonist.

Product Specific Literature References

Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord: D.E. Jane, et al.; Neuropharmacology 35, 1029 (1996) Abstract
Group 1 and 2 metabotropic glutamate receptors play differential roles in hippocampal long-term depression and long-term potentiation in freely moving rats: D. Manahan-Vaughan; J. Neurosci. 17, 3303 (1997) Abstract
Bidirectional synaptic plasticity in the rat basolateral amygdala: characterization of an activity-dependent switch sensitive to the presynaptic metabotropic glutamate receptor antagonist 2S-alpha-eth: H. Li, et al.; J. Neurosci. 18, 1662 (1998) Abstract
Induction of long-lasting depression by (+)-alpha-methyl-4-carboxyphenylglycine and other group II mGlu receptor ligands in the dentate gyrus of the hippocampus in vitro: L. Huang, et al.; Eur. J. Pharmacol. 366, 151 (1999) Abstract
Pharmacological agents acting at subtypes of metabotropic glutamate receptors: D.D. Schoepp, et al.; Neuropharmacology 38, 1431 (1999), (Review) Abstract

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