ALEXIS Biochemicals: (2S,5S)-8-Decylbenzolactam V

ALX-270-261

Revised 14-May-03

(2S,5S)-8-Decylbenzolactam V
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	PKC Activators

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-261-C500		500 µg	125.00 USD

Product Specification

FORMULA:	C₂₅H₄₂N₂O₂
MW:	402.6
PURITY:	≥95%
APPEARANCE:	Oil.
SOLUBILITY:	Soluble in ethanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Activator of protein kinase C (PKC) with improved selectivity for the α, β and γ isoforms.

Product Specific Literature References

Modeling, chemistry, and biology of the benzolactam analogues of indolactam V (ILV). 2. Identification of the binding site of the benzolactams in the CRD2 activator-binding domain of PKCdelta: A.P. Kozikowski, et al.; J. Med. Chem. 40, 1316 (1997) Abstract
Restoration of TEA-induced calcium responses in fibroblasts from Alzheimer's disease patients by a PKC activator: S. Bhagavan, et al.; Neurobiol. Dis. 5, 177 (1998) Abstract

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