ALEXIS Biochemicals: 3-ATA

ALX-350-273

Revised 03-Apr-08

3-ATA
SYNONYMS	3-Amino-9-thio(10H)-acridone
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products for Cell Cycle Research

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-273-M001		1 mg	60.00 USD
ALX-350-273-M005		5 mg	240.00 USD

Product Specification

FORMULA:	C₁₃H₁₀N₂S
MW:	226.3
CAS NUMBER:	12982-10-85
PURITY:	≥95%
APPEARANCE:	White solid powder.
SOLUBILITY:	Soluble in DMSO or dimethyl formamide.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+20°C

Product Description

Specific CDK4 inhibitor (IC₅₀=3.1µM) inducing growth inhibition of p16-altered tumors.

Product Specific Literature References

The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4: A. Kubo, et al.; Clin. Cancer Res. 5, 4279 (1999) Abstract
3-Amino thioacridone, a selective cyclin-dependent kinase 4 inhibitor, attenuates kainic acid-induced apoptosis in neurons: E. Verdaguer, et al.; Neuroscience 120, 599 (2003) Abstract

Further Categories Containing This Product:

CDK & Cyclin Inhibitors

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