ALEXIS Biochemicals: 3-Amino-1H-pyrazolo[3,4-b]quinoxaline

ALX-270-387

Revised 18-Jul-07

3-Amino-1H-pyrazolo[3,4-b]quinoxaline
PRODUCT LINE	Cell Cycle
PRODUCT CATEGORY	CDK & Cyclin Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-387-M001		1 mg	40.00 USD
ALX-270-387-M005		5 mg	160.00 USD

Product Specification

FORMULA:	C₉H₇N₅
MW:	185.2
CAS NUMBER:	40254-90-8
PURITY:	≥98% (HPLC)
APPEARANCE:	Red solid.
SOLUBILITY:	Soluble in DMSO.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	+4°C
HANDLING:	Protect from light. Packaged under inert gas.

Product Description

Selective inhibitor of CDK1/cyclin B (IC₅₀=600nM), CDK5/p25 (IC₅₀=400nM) and GSK-3β (IC₅₀=1µM). Does not inhibit Cdc25 phosphatase activity (IC₅₀>10µM).

Product Specific Literature References

Pyrazolo[3,4-b]quinoxalines. A new class of cyclin-dependent kinases inhibitors: M.A. Ortega, et al.; Bioorg. Med. Chem. 10, 2177 (2002) Abstract

Further Categories Containing This Product:

GSK-3 Inhibitors

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