ALEXIS Biochemicals: 3-Nitro-L-tyrosine

ALX-106-020

Revised 28-Jan-05

3-Nitro-L-tyrosine
PRODUCT LINE	Nitric Oxide Pathway
PRODUCT CATEGORY	Nitrotyrosine / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-106-020-G001		1 g	25.00 USD
ALX-106-020-G005		5 g	90.00 USD

Product Specification

FORMULA:	C₉H₁₀N₂O₅
MW:	226.2
CAS NUMBER:	621-44-3
PURITY:	≥98%
APPEARANCE:	Yellow to yellow-green powder.
SOLUBILITY:	Soluble in acidic aqueous solution (e. g. 1N hydrochloric acid).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+20°C

Product Description

Nitrotyrosine is the major product from the spontaneous reaction of peroxynitrite with tyrosine. Formation of nitrotyrosine in vivo can indicate the formation of peroxynitrite by a nitric oxide (NO)-dependent oxidative damage.

Product Specific Literature References

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase: H. Ischiropoulos, et al.; Arch. Biochem. Biophys. 298, 431 (1992) Abstract
Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry: J.S. Beckman, et al.; Biol. Chem. Hoppe-Seyler 375, 81 (1994) Abstract
Peroxynitrite-mediated oxidative protein modifications: H. Ischiropoulos & A.B. Al-Mehdi; FEBS Lett. 364, 279 (1995) Abstract
Detection and quantitation of nitrotyrosine residues in proteins: in vivo marker of peroxynitrite: J.P. Crow, et al.; Meth. Enzymol. 269, 185 (1996) Abstract
Antibodies that recognize nitrotyrosine: Y.Z. Ye, et al.; Meth. Enzymol. 269, 201 (1996) Abstract

Further Categories Containing This Product:

Special Amino Acids

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