Tetrahydrobiopterin binding to macrophage inducible nitric oxide synthase: heme spin shift and dimer stabilization by the potent pterin antagonist 4-amino-tetrahydrobiopterin: B. Mayer, et al.; Biochemistry 36, 8422 (1997) Abstract
Allosteric modulation of rat brain nitric oxide synthase by the pterin-site enzyme inhibitor 4-aminotetrahydrobiopterin: S. Pfeiffer, et al.; Biochem. J. 328, 349 (1997) Abstract; Full Text
Preferential inhibition of inducible nitric oxide synthase in intact cells by the 4-amino analogue of tetrahydrobiopterin: K. Schmidt, et al.; Eur. J. Biochem. 259, 25 (1999) Abstract; Full Text
Protection against endotoxemia in rats by a novel tetrahydrobiopterin analogue: S. Bahrami, et al.; Shock 13, 386 (2000) Abstract
Inhibition of endotoxin-induced vascular hyporeactivity by 4-amino-tetrahydrobiopterin: H.D. Gibraeil, et al.; Br. J. Pharmacol. 131, 1757 (2000) Abstract
The 4-amino analogue of tetrahydrobiopterin efficiently prolongs murine cardiac-allograft survival: G. Brandacher, et al.; J. Heart Lung Transplant. 20, 747 (2001) Abstract
A 4-amino analogue of tetrahydrobiopterin attenuates endotoxin-induced hemodynamic alterations and organ injury in rats: F. Fitzal, et al.; Shock 18, 158 (2002) Abstract
Biopterin analogues: novel nitric oxide synthase inhibitors with immunosuppressive action: E.R. Werner and G. Werner-Felmayer; Curr. Drug Metab. 3, 119 (2002), (Review) Abstract
Single-turnover of nitric-oxide synthase in the presence of 4-amino-tetrahydrobiopterin: proposed role for tetrahydrobiopterin as a proton donor: M. Sorlie, et al.; J. Biol. Chem. 278, 48602 (2003) Abstract; Full Text
Ability of tetrahydrobiopterin analogues to support catalysis by inducible nitric oxide synthase: formation of a pterin radical is required for enzyme activity: A.R. Hurshman, et al.; Biochemistry 42, 13287 (2003) Abstract
CO exchange of the oxyferrous complexes of endothelial nitric-oxide synthase oxygenase domain in the presence of 4-amino-tetrahydrobiopterin: S. Marchal, et al.; J. Inorg. Biochem. 98, 1217 (2004) Abstract
Tetrahydropteridines suppress gene expression and induce apoptosis of activated RAW264.7 cells via formation of hydrogen peroxide: G. Thoeni, et al.; Free Radic. Biol. Med. 37, 375 (2004) Abstract
Tetrahydro-4-aminobiopterin attenuates dendritic cell-induced T cell priming independently from inducible nitric oxide synthase: G. Thoeni, et al.; J. Immunol. 174, 7584 (2005) Abstract; Full Text
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