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ALX-550-141 Revised 17-Jan-05
4-Aminopyridine
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SYNONYMS Fampridine
4-Pyridylamine
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY K+ Channel Blockers & Inhibitors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-550-141-G005   5 g 20.00 USD Add To Cart
Product Specification
FORMULA: C5H6N2
MW: 94.1
CAS NUMBER: 504-24-5
MERCK INDEX: 14: 3933
PURITY: ≥98%
APPEARANCE: Off-white solid.
SOLUBILITY: Soluble in water or 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HANDLING: Protect from light.
HAZARD: TOXIC.

Product Description
Induces depolarization of GABA neurons. Non-selective K+ channel blocker. Reverses saxitoxin- and tetrodotoxin-induced cardiorespiratory depression. Increases stimulation-induced release of acetylcholine.
Product Specific Literature References
Effects of 4-aminopyridine on normal and demyelinated mammalian nerve fibres: R.M. Sherratt, et al.; Nature 283, 570 (1980) Abstract
The origin, structure, and pharmacological activity of botulinum toxin: L.L. Simpson; Pharmacol. Rev. 33, 155 (1981) Abstract
Further Categories Containing This Product:
GABA-ergics & GABA Receptors / Related Products
 
 
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