ALEXIS Biochemicals: 4-Bromo-A23187

ALX-450-003

Revised 03-Apr-08

4-Bromo-A23187
SYNONYMS	4-Bromo-Calcimycin 4-Bromo-Calcium Ionophore A23187
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics - Ionophores

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-450-003-M001		1 mg	85.00 USD
ALX-450-003-M005		5 mg	260.00 USD

Product Specification

FORMULA:	C₂₉H₃₆BrN₃O₆
MW:	602.5
CAS NUMBER:	76455-82-8
SOURCE/HOST:	Semisynthetic.
PURITY:	≥85%
APPEARANCE:	Yellow solid.
SOLUBILITY:	Soluble in methanol or methylene chloride.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HANDLING:	Protect from light and moisture.
HAZARD:	TOXIC.

Product Description

Brominated analog of the widely used calcium ionophore A23187 (Prod. No. ALX-450-001). Nonfluorescent, and therefore used as a calibration standard for determining cytoplasmic calcium ions by fluorescent probes.

Product Specific Literature References

Bromo-A23187: a nonfluorescent calcium ionophore for use with fluorescent probes: C.M. Deber, et al.; Anal. Biochem. 146, 349 (1985) Abstract
Calcium transport by ionophorous peptides in dog and human lymphocytes detected by quin-2 fluorescence: C.M. Deber & L.C. Hsu; BBRC 134, 731 (1986) Abstract
Ionophore bromo-A23187 reveals cellular calcium stores in single pituitary somatotropes
: R.W. Holl, et al.; Mol. Cell. Endocrinol. 64, 105 (1989) Abstract
The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187
: T. Qian, et al.; Toxicol. Appl. Pharmacol. 154, 117 (1999) Abstract

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