ALEXIS Biochemicals: 5-AIQ . hydrochloride

ALX-270-285

Revised 11-Aug-06

5-AIQ . hydrochloride
SYNONYMS	5-Aminoisoquinolinone . HCl
PRODUCT LINE	DNA Regulation / Transcription
PRODUCT CATEGORY	DNA Repair Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-285-M001		1 mg	50.00 USD
ALX-270-285-M005		5 mg	175.00 USD

Product Specification

FORMULA:	C₉H₈N₂O . HCl
MW:	160.2 . 36.5
PURITY:	≥97%
APPEARANCE:	Beige to brown powder.
SOLUBILITY:	Soluble in water (warm).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HANDLING:	Protect from moisture.
HAZARD:	IRRITANT.

Product Description

Water-soluble, potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1).

Product Specific Literature References

Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock: M.C. McDonald, et al.; Br. J. Pharmacol. 130, 843 (2000) Abstract
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury: S. Cuzzocrea, et al.; Biochem. Pharmacol. 63, 293 (2002) Abstract

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