ALEXIS Biochemicals: 5-Aminosalicylic acid

ALX-430-110

Revised 16-Jan-08

5-Aminosalicylic acid
SYNONYMS	5-ASA Mesalamine 5-Amino-2-hydroxybenzoic acid
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	NF-kB Pathway Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-430-110-G005		5 g	20.00 USD

Product Specification

FORMULA:	C₇H₇NO₃
MW:	153.1
CAS NUMBER:	89-57-6
MERCK INDEX:	14: 5904
PURITY:	≥98%
SOLUBILITY:	Soluble in 1 M hydrochloric acid.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C

Product Description

Inhibits TNF-α regulated IκB degradation and NF-κB activation.

Product Specific Literature References

Inhibition of nuclear factor kappa B and induction of apoptosis in T-lymphocytes by sulfasalazine: S. Liptay, et al.; Br. J. Pharmacol. 128, 1361 (1999) Abstract
Aminosalicylic acid inhibits IkappaB kinase alpha phosphorylation of IkappaBalpha in mouse intestinal epithelial cells: F. Yan & D.B. Polk; J. Biol. Chem. 274, 36631 (1999) Abstract; Full Text

Further Categories Containing This Product:

Non-Steroidal Anti-Inflammatory Drugs [NSAIDS]

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