ALEXIS Biochemicals: 5-Iodocytidine

ALX-480-098

Revised 14-Dec-07

5-Iodocytidine
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Cytidine Derivatives Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-480-098-M005		5 mg	70.00 USD
ALX-480-098-M025		25 mg	280.00 USD

Product Specification

FORMULA:	C₉H₁₂IN₃O₅
MW:	369.1
CAS NUMBER:	1147-23-5
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white crystalline solid.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
IDENTITY:	Determined by MS and UV.

Product Description

Key tool for research in the field of nucleic acids and nucleic acid-protein interactions. Has been used in structural elucidation of mispairs with natural bases to explain their mutagenic properties; in the study of cytosine methyltransferases; for photo-crosslinking of nucleoprotein complexes; in X-ray diffraction experiments of nucleic acids and nucleic acid binding proteins; as nonradioactive label and as alternative for mixed probes; for triple-helix stabilization; as antisense oligonucleotide; and in the study of the restriction endonucleases cleavage mechanism.

Product Specific Literature References

Complex of aspartate carbamoyltransferase from Escherichia coli with its allosteric inhibitor, cytidine triphosphate: electron density at 5.9-angstroms resolution: B.F. Edwards, et al.; PNAS 71, 4437 (1974) Abstract; Full Text
Properties of phenylalanine transfer ribonucleic acid with modified 3’-terminal end in protein biosynthesis using a rabbit reticulocyte cell-free system: effect of the replacement of cytidine residues from the CpCpA end of tRNA by 5-iodocytidine or : E.K. Baksht, et al.; Nucl. Acids Res. 4, 2205 (1977) Abstract; Full Text
Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins: M.C. Willis, et al.; Science 262, 1255 (1993) Abstract
High yield photocrosslinking of a 5-iodocytidine (IC) substituted RNA to its associated protein: K.M. Meisenheimer, et al.; Nucl. Acids Res. 24, 981 (1996) Abstract; Full Text
Preparation and properties of oligodeoxynucleotides containing 5-iodouracil and 5-bromo- and 5-iodocytosine: E. Ferrer, et al.; Bioconjug. Chem. 8, 757 (1997) Abstract

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