ALEXIS Biochemicals: 5’,6’-Epoxyeicosatrienoic acid

ALX-340-059

Revised 10-Jul-08

5’,6’-Epoxyeicosatrienoic acid
SYNONYMS	(±)-5(6)-Epoxy-8Z,11Z,14Z-eicosatrienoic acid 5',6'-EET
PRODUCT LINE	Neurobiology
PRODUCT CATEGORY	TRPV2, TRPV3, TRPV4 / Related Products

Ordering Information

Product Specification

FORMULA:	C₂₀H₃₂O₃
MW:	320.5
CONCENTRATION:	0.1mg/ml
PURITY:	≥98%
FORMULATION:	Liquid. Solution in acetonitrile.
SOLUBILITY:	50mg/ml soluble in 100% ethanol, DMSO or dimethyl formamide; slightly soluble in PBS, pH 7.2 (1mg/ml).
SHIPPING:	SHIPPED ON DRY ICE
LONG TERM STORAGE:	-80°C
USE/STABILITY:	Stable for at least 6 months after receipt when stored at -80°C. Keep aqueous solutions on ice and use within 12 hours.

Product Description

Endogenous TRPV4 agonist (K_i=150nM).

Product Specific Literature References

Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels: H. Watanabe, et al.; Nature 424, 434 (2003) Abstract

General Information

BACKGROUND/TECHNICAL INFORMATION

To change the solvent, evaporate the acetonitrile under a gentle stream of nitrogen and immediately add the solvent of choice.

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