ALEXIS Biochemicals: 6’-Iodononivamide

ALX-350-122

Revised 07-Apr-08

6’-Iodononivamide
SYNONYMS	6-Iodonordihydrocapsaicin N-(4-Hydroxy-6-iodo- 3-methoxybenzyl)nonanamide
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Neurotoxins

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-122-M005		5 mg	60.00 USD
ALX-350-122-M010		10 mg	95.00 USD

Product Specification

FORMULA:	C₁₇H₂₆INO₃
MW:	419.3
PURITY:	≥99% (HPLC)
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in 100% ethanol or DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.

Product Description

Potent competitive TRPV1 antagonist (IC₅₀=10nM against 100nM capsaicin; Prod. No. ALX-550-066). Convenient replacement for capsazepine (Prod. No. ALX-550-145) in most of the in vitro preparations currently used to assess the activity of putative vanilloid receptor agonists.

Product Specific Literature References

Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists: G. Appendino, et al.; Br. J. Pharmacol. 139, 1417 (2003) Abstract
The taming of capsaicin. Reversal of the vanilloid activity of N-acylvanillamines by aromatic iodination: G. Appendino, et al.; J. Med. Chem. 48, 4663 (2005) Abstract

Further Categories Containing This Product:

TRPV1 Agonists and Antagonists / Related Products

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