ALEXIS Biochemicals: 7-Chlorothiokynurenic acid . hydrochloride

ALX-550-067

Revised 06-Dec-04

7-Chlorothiokynurenic acid . hydrochloride
SYNONYMS	7-Chloro-4-mercaptoquinoline-2-carboxylic acid . HCl
PRODUCT LINE	Neurobiology
PRODUCT CATEGORY	NMDA Receptors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-550-067-M005		5 mg	55.00 USD

Product Specification

FORMULA:	C₁₀H₆ClNO₂S . HCl
MW:	239.7 . 36.5
CAS NUMBER:	135025-56-8
PURITY:	≥99%
APPEARANCE:	Yellow powder.
SOLUBILITY:	Soluble in DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+20°C

Product Description

NMDA receptor antagonist acting at the glycine site. More potent than the corresponding kynurenic acid analog (Prod. No. ALX-550-070).

Product Specific Literature References

Thiokynurenates: a new group of antagonists of the glycine modulatory site of the NMDA receptor: F. Moroni, et al.; Eur. J. Pharmacol. 199, 227 (1991) Abstract
A study of the dose dependency of a glycine receptor antagonist in focal ischemia: J. Chen, et al.; J. Pharmacol. Exp. Ther. 267, 937 (1993) Abstract
The glycine antagonist and free radical scavenger 7-Cl-thio-kynurenate reduces CA1 ischemic damage in the gerbil: D.E. Pellegrini-Giampietro, et al.; Neuroscience 63, 701 (1994) Abstract

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