ALEXIS Biochemicals: 8-Bromoadenosine 3',5'-cyclic Monophosphothioate, Sp-Isomer . sodium salt

ALX-480-025

Revised 26-Jul-06

8-Bromoadenosine 3',5'-cyclic Monophosphothioate, Sp-Isomer . sodium salt
SYNONYMS	Sp-8-Br-cAMPS . Na 8-Br-cAMPS . Na, Sp-isomer
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	cAMP Derivatives

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-480-025-M001		1 mg	140.00 USD
ALX-480-025-M005		5 mg	560.00 USD

Product Specification

FORMULA:	C₁₀H₁₀BrN₅O₅PS . Na
MW:	423.2 . 23.0
CAS NUMBER:	127634-20-2
PURITY:	≥99%
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in water or aqueous buffer.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Metabolically resistant activator of cAMP-dependent protein kinase (PKA) (cAMP agonist). No metabolic side effects as observed with dibutyryl-cAMP (N⁶,O^2'-Dibutyryladenosine 3',5'-cyclic monophosphate, Prod. No. ALX-480-045) or 8-Br-cAMP (8-Bromoadenosine-3',5'-cyclic monophosphate, Prod. No. ALX-480-007). Significantly more lipophilic and membrane permeant as compared to Sp-cAMPS (Adenosine 3',5'-cyclic monophosphothioate, Sp isomer, Prod. No. ALX-480-013).

Product Specific Literature References

Cell-permeable non-hydrolyzable cAMP derivatives as tools for analysis of signaling pathways controlling gene regulation in Dictyostelium: P. Schaap, et al.; J. Biol. Chem. 268, 6323 (1993) Abstract; Full Text

Further Categories Containing This Product:

PKA Activators

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