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ALX-480-058 Revised 18-Jun-08
8-Nitroguanine
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Nucleobases
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-480-058-M001   1 mg 120.00 USD Add To Cart
Product Specification
FORMULA: C5H4N6O3
MW: 196.1
CAS NUMBER: 168701-80-2
PURITY: ≥98% (HPLC)
SOLUBILITY: Slightly soluble in water (sonification).
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
IDENTITY: Identity determined by 1H-NMR, MS and UV.

Product Description
Oxidative DNA degradation product.
Product Specific Literature References
Formation of 8-nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination: V. Yermilov, et al.; FEBS Lett. 376, 207 (1995) Abstract
Antioxidant and pro-oxidant actions of flavonoids: effects on DNA damage induced by nitric oxide, peroxynitrite and nitroxyl anion: H. Ohshima, et al.; Free Radic. Biol. Med. 25, 1057 (1998) Abstract
Importance of guanine nitration and hydroxylation in DNA in vitro and in vivo: J. Tuo, et al.; Free Radic. Biol. Med. 29, 147 (2000) Abstract
 
 

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