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ALX-260-095 Revised 04-Mar-05
α-MAPI
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Proteases Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-260-095-M001   1 mg 80.00 USD Add To Cart
ALX-260-095-M005   5 mg 240.00 USD Add To Cart
Product Specification
FORMULA: C30H41N7O6
MW: 595.7
SOURCE/HOST: Synthetic.
PURITY: ≥95%
APPEARANCE: White powder.
SOLUBILITY: Soluble in methanol; soluble in water (2mg/ml) after sonification.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Microbial alkaline proteinase inhibitor (α-MAPI) binds strongly to the active site of the HIV protease.
Product Specific Literature References
Structural elucidation of alpha-MAPI, a novel microbial alkaline proteinase inhibitor, produced by Streptomyces nigrescens: T. Watanabe, et al.; THL 7, 625 (1979)
A high throughput assay for inhibitors of HIV-1 protease. Screening of microbial metabolites: E. Sarubbi, et al.; FEBS Lett. 279, 265 (1991) Abstract
First efficient synthesis of alpha-MAPI: R.J. Broadbridge, et al.; Chem. Commun. 1998, 1449
 
 
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