ALEXIS Biochemicals: β-Nerve Growth Factor (human) (recombinant)

ALX-521-005

Revised 20-Oct-08

β-Nerve Growth Factor (human) (recombinant)
SYNONYMS	β-NGF (human) (recombinant)
PRODUCT LINE	Chemokines & Cytokines
PRODUCT CATEGORY	Nerve Growth Factors [NGF] & Receptors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-521-005-C005		5 µg	140.00 USD

Product Specification

MW:	~27kDa (dimer).
CAS NUMBER:	86923-98-0
SOURCE/HOST:	Produced in E. coli. Dimer of two identical subunits (119 aa) linked together by very strong hydrophobic interactions.
QUANTITY:	5µg (determined by amino acid analysis).
PURITY:	≥98% (HPLC)
FORMULATION:	Lyophilized. No additives.
RECONSTITUTION:	Reconstitue in water or DMEM to a final concentration of at least 10µg/ml and store at -80°C before use.
BIOLOGICAL ACTIVITY:	Neurotrophic activity was bioassayed using rat pheochromocytoma PC12 cell cultures over a period of 7-14 days. Activity is in the range of 1-50ng/ml.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Lyophilized protein is stable for 2-3 weeks when stored at room temperature and for 6-9 months when stored at -20°C. Reconstituted protein is stable for up to 1 week when stored at +4°C and for 4-6 weeks when stored at 80°C.
HANDLING:	Avoid freeze/thaw cycles.

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General Information

Human β-NGF is responsible for survival, differentiation and maturation of sympathetic and sensory neurons.

General Literature References

The changing scene of neurotrophic factors : H. Thoenen; TINS 14, 165 (1991), (Review) Abstract
Towards a comprehensive understanding of the trophic support of motoneurons: H. Thoenen, et al.; C.R. Acad. Sci. III 316, 1158 (1193), (Review) Abstract
Neurotrophic factors enter the clinic: M. Barinaga; Science 264, 772 (1994), (Review) Abstract
Neurobiology. Tracking neurotrophin function: A.M. Davies; Nature 368, 193 (1994), (Review) Abstract
Role of neurotrophins in mouse neuronal development: R. Klein; FASEB J. 8, 738 (1994), (Review) Abstract
The neurotrophins and their receptors: structure, function, and neuropathology: L.M. Maness, et al.; Neurosci. & Biobehav. Rev. 18, 143 (1994), (Review) Abstract
Neurotrophic factors: two are better than one : R. Nishi; Science 265, 1052 (1994), (Review) Abstract

Further Categories Containing This Product:

Recombinant Proteins / Fusion Proteins

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