ALEXIS Biochemicals: Ac-IETD-CHO

ALX-260-043

Revised 13-Nov-06

Ac-IETD-CHO
SYNONYMS	Caspase-8 Inhibitor (Aldehyde) Granzyme B Inhibitor (Aldehyde)
PRODUCT LINE	Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY	Caspase Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-260-043-M001		1 mg	62.00 USD
ALX-260-043-M005		5 mg	243.00 USD

Product Specification

SEQUENCE:	Ac-Ile-Glu-Thr-Asp-CHO
FORMULA:	C₂₁H₃₄N₄O₁₀
MW:	502.5
PEPTIDE CONTENT:	70-90%.
PURITY:	≥97% (HPLC)
FORMULATION:	Lyophilized.
SOLUBILITY:	Soluble in DMSO. Dilute with buffer, pH 7.5.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Use always fresh solutions.
HANDLING:	Keep cool and dry.

Product Description

Reversible inhibitor of caspase-8 and granzyme B. Also inhibits caspase-10.

Product Specific Literature References

A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro: Z. Han, et al.; J. Biol. Chem. 272, 13432 (1997) Abstract; Full Text

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