ALEXIS Biochemicals: Ac-TQTD-AFC

ALX-260-161

Revised 02-Mar-06

Ac-TQTD-AFC
SYNONYMS	DRONC Substrate II (Fluorogenic) Drosophila Caspase Substrate II (Fluorogenic)
PRODUCT LINE	Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY	Caspase Substrates

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-260-161-M001		1 mg	35.00 USD
ALX-260-161-M005		5 mg	140.00 USD

Product Specification

SEQUENCE:	Ac-Thr-Gln-Thr-Asp-AFC (AFC=7-Amino-4-trifluoromethylcoumarin)
FORMULA:	C₂₉H₃₅F₃N₆O₁₂
MW:	716.6
PURITY:	≥97% (HPLC)
APPEARANCE:	Lyophilized.
SOLUBILITY:	Soluble in DMSO. Dilute with buffer, pH 7.0 or higher.
SHIPPING:	AMBIENT
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
HANDLING:	Packaged under inert gas. Protect from light.

Product Specific Literature References

A cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1: C.J. Hawkins, et al.; PNAS 96, 2885 (1999) Abstract
The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM: C.J. Hawkins, et al.; J. Biol. Chem. 275, 27084 (2000) Abstract

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