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ALX-380-202 Revised 28-May-08
Anguinomycin A
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SYNONYMS 5-Demethylleptomycin A
KR 2827A
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Antitumor Antibiotics
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-380-202-MC01   0.1 mg 460.00 USD Add To Cart
Product Specification
FORMULA: C31H44O6
MW: 512.7
CAS NUMBER: 111278-01-4
SOURCE/HOST: Isolated from Streptomyces sp. MST-AS5546.
PURITY: ≥95% (HPLC)
APPEARANCE: Clear film.
SOLUBILITY: Soluble in 100% ethanol (recommended) or methanol. Unstable in DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Antitumor antibiotic. Displays nanomolar cytotoxicity to murine P388 leukemia cells. Analog of leptomycin B (Prod. No. ALX-380-100), an inhibitor of nuclear protein export.
Product Specific Literature References
New antitumor antibiotics, anguinomycins A and B: Y. Hayakawa, et al.; J. Antibiot. (Tokyo) 40, 1349 (1987) Abstract
Anguinomycins C and D, new antitumor antibiotics with selective cytotoxicity against transformed cells: Y. Hayakawa, et al.; J. Antibiot. (Tokyo) 48, 954 (1995) Abstract
 
 
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