ALEXIS Biochemicals: Aspyrone

ALX-380-121

Revised 03-Apr-08

Aspyrone
SYNONYMS	5,6-Dihydro-5-hydroxy-6-methyl-3-(3-methyloxiranyl)-2H-pyran-2-one 3-(1,2-Epoxypropyl)-5,6-dihydro-5-hydroxy-6-methyl-2H-pyran-2-one
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics - Antifungal

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-121-M001		1 mg	60.00 USD
ALX-380-121-M005		5 mg	240.00 USD

Product Specification

FORMULA:	C₉H₁₂O₄
MW:	184.2
CAS NUMBER:	17398-00-4
SOURCE/HOST:	Isolated from Aspergillus ochraceus.
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in DMSO, methanol or acetone.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from moisture.

Product Description

Antibiotic with nematicidal, insecticidal, antibacterial and antifungal activity.

Product Specific Literature References

A new metabolite of Aspergillus melleus: S.D. Mills & W.B. Turner; J. Chem. Soc. (C) 1967, 2242 (1967)
Production of 3-(1,2-Epoxypropyl)-5,6-dihydro-5-hydroxy-6-methylpyran-2-one by Aspergillus ochraceus Wilhelm: J.H. Moore, et al.; J. Agr. Food Chem. 22, 697 (1974) Abstract
J.S.E. Holker, et al.; J.C.S. Perkin Trans. I 1981, 1397 (1981)
17O NMR in biosynthetic studies: aspyrone, asperlactone and isoasperlactone, metabolites of Aspergillus melleus: J. Staunton & A.C. Sutkowski; J.C.S. Chem. Commun. 1991, 1106 (1991)
Biosynthesis of aspyrone, a metabolite of Aspergillus melleus: advanced precursor studies to identify the product of the polyketide synthase: J. Staunton & A.C. Sutkowski; J.C.S. Chem. Commun. 1991, 1108 (1991)
The polyketide synthase (PKS) of aspyrone biosynthesis: evidence for the enzyme bound intermediates from incorporation studies with N-acetylcysteamine thioesters in intact cells of Aspergillus melleus: J. Staunton & A.C. Sutkowski; J.C.S. Chem. Commun. 1991, 1110 (1991)
Effect of fungal metabolites and some derivatives against Tribolium castaneum (Herbst) and Nezara viridula (L.): M. Balcells, et al.; Pestic. Sci. 45, 319 (1995)
Synthesis of chiral aspyrone, a multi-functional dihydropyranone antibiotic: T. Sugiyama, et al.; Biosci. Biotech. Biochem. 59, 1921 (1995) Abstract
Aspyrone, a nematicidal compound isolated from the fungus, Aspergillus melleus: Y. Kimura, et al.; Biosci. Biotech. Biochem. 60, 1375 (1996)
Bactericidal and fungicidal activity of Aspergillus ochraceus metabolites and some derivatives: M. Torres, et al.; Pestic. Sci. 53, 9 (1998)

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