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ALX-270-487 Revised 22-Jul-08 New product
BML-259
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SYNONYMS N-(5-Isopropylthiazol-2-yl)phenylacetamide
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY CDK & Cyclin Inhibitors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-270-487-M005   5 mg 70.00 USD Add To Cart
Product Specification
FORMULA: C14H16N2OS
MW: 260.4
CAS NUMBER: 267654-00-2
PURITY: ≥98% (TLC)
APPEARANCE: White to off-white solid.
SOLUBILITY: 30mg/ml soluble in DMSO or dimethyl formamide, 0.25mg/ml soluble in 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
USE/STABILITY: Stock solutions are stable for up to 3 months when stored at -20°C.

Product Description
Potent inhibitor of CDK5 (IC50 = 64nM) and CDK2 / cyclin E (IC50 = 98nM).
Product Specific Literature References
Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease: C.J. Helal, et al.; Bioorg. Med. Chem. Lett. 14, 5521 (2004) Abstract
 
 
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