ALEXIS Biochemicals: BPIQ-II

ALX-270-338

Revised 03-Mar-05

BPIQ-II
SYNONYMS	8-[(3-Bromophenyl)amino]-1H-imidazo[4,5-γ]-quinazoline
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	EGFR Kinase Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-338-M001		1 mg	140.00 USD

Product Specification

FORMULA:	C₁₅H₁₀BrN₅
MW:	340.2
PURITY:	≥98%
APPEARANCE:	Pale pink solid.
SOLUBILITY:	Soluble in DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light. Keep under inert gas.

Product Description

Potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (IC₅₀=8pM).

Product Specific Literature References

Tyrosine kinase inhibitors. 9. Synthesis and evaluation of fused tricyclic quinazoline analogues as ATP site inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor: G.W. Rewcastle, et al.; J. Med. Chem. 39, 918 (1996) Abstract

Further Categories Containing This Product:

Tyrosine Kinase Inhibitors

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