ALEXIS Biochemicals: Benzamide

ALX-270-174

Revised 20-Oct-08

Benzamide
PRODUCT LINE	DNA Regulation / Transcription
PRODUCT CATEGORY	PARP Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-174-G005		5 g	20.00 USD

Product Specification

FORMULA:	C₇H₇NO
MW:	121.1
CAS NUMBER:	55-21-0
MERCK INDEX:	14: 1060
RTECS:	CU8700000
PURITY:	≥99%
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in 100% ethanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+20°C
HAZARD:	HARMFUL.

Product Description

Inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1). Neuroprotectant.

Product Specific Literature References

Cytotoxicity of a new IMP dehydrogenase inhibitor, benzamide riboside, to human myelogenous leukemia K562 cells: H.N. Jayaram, et al.; BBRC 186, 1600 (1992) Abstract
Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity: J. Zhang, et al.; Science 263, 687 (1994) Abstract
Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation: H. Kleine, et al.; Mol. Cell 32, 57 (2008) Abstract

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