ALEXIS Biochemicals: Bisindolylmaleimide III

ALX-270-051

Revised 18-Jan-08

Bisindolylmaleimide III
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	PKC Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-051-M001		1 mg	45.00 USD
ALX-270-051-M005		5 mg	150.00 USD

Product Specification

FORMULA:	C₂₃H₂₀N₄O₂
MW:	384.4
PURITY:	≥98%
APPEARANCE:	Red solid.
SOLUBILITY:	Soluble in methanol or DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.

Product Description

Potent and selective inhibitor of protein kinase C (PKC).

Product Specific Literature References

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C: D. Toullec, et al.; J. Biol. Chem. 266, 15771 (1991) Abstract; Full Text
Protein kinase C inhibitors; structure-activity relationships in K252c- related compounds: S. Fabre and M. Prudhomme; Bioorg. Med. Chem. 1, 193 (1993) Abstract
Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides: P.D. Davis, et al.; J. Med. Chem. 35, 177 (1992) Abstract
Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors: D. Brehmer, et al.; Mol. Cell Proteomics 3, 490 (2004) Abstract; Full Text

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