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TRAP5 [TRACP]
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ALX-804-533 Revised 20-Feb-07
Monoclonal Antibody to TRAP5 (human) (TRAP-01)
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SYNONYMS anti-Tartrate-resistant Acid Phosphatase 5 (human) MAb (TRAP-01)
anti-TRACP (human) MAb (TRAP-01)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY TRAP5 [TRACP]
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-533-C100   100 µg 508.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: TRAP-01
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml after reconstitution.
PURITY DETAIL: Protein G-affinity purified. Sterile filtered.
FORMULATION: Lyophilized from PBS, pH 7.4.
RECONSTITUTION: Reconstitute with 100µl of distilled water. Activity is not affected by slight turbidity. Clarify by centrifugation.
IMMUNOGEN: Recombinant human TRAP5 (tartrate-resistant acid phosphatase 5).
SPECIFICITY: Recognizes human TRAP5.
APPLICATION: ELISA
ImmunoCapture Enzyme-Activity Assay
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
HANDLING: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C.
Product Specific Literature References
[1] Purification and N-terminal sequence of two tartrate-resistant acid phosphatases type-5 from the hairy cell leukemia spleen: J.J. Stepan, et al.; BBRC 165, 1027 (1989) Abstract
[2] Tartrate-resistant acid phosphatase 5b: a novel serum marker of bone resorption: J.M. Halleen, et al.; J. Bone Miner. Res 15, 1337 (2000) Abstract
[3] Tartrate-resistant acid phosphatase isoform 5b as serum marker for osteoclastic activity: A.J. Janckila, et al.; Clin. Chem. 47, 74 (2001) Abstract
[4] Clinical performance of immunoreactive tartrate-resistant acid phosphatase isoform 5b as a marker of bone resorption: R.A. Hannon, et al.; Bone 34, 187 (2004) Abstract
[5] TRACP as an osteopontin phosphatase: G. Andersson, et al.; J. Bone Miner. Res 18, 1912 (2003) Abstract
General Information
TRAP5b is claimed to be a specific marker of bone resorption [2-4]. Both osteopontin and bone sialoprotein are colocalized with TRAP5 in the resorption lacuna of osteoclasts and dephosphorylation of osteopontin impair its ability to promote adhesion as well as migration of osteoclasts in vitro [5].
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-850-300 Revised 25-Sep-08
TRAP5 (human) ImmunoCapture Enzyme-Activity Assay Kit
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY TRAP5 [TRACP]
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-850-300-KI01   1 Kit 852.00 USD Add To Cart
Product Specification
SENSITIVITY: 0.4U/l (range 0.2 to 4U/l)
QUANTITY: 96 wells (~80 tests)
APPLICATION: For the quantitative determination of human TRAP5 in serum and plasma. The kit measures only the TRAP5 proteins exhibiting enzymatic activity. Weakly cross-reacts with dog, monkey and rabbit TRAP5. Does not cross-react with mouse and rat sera.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
TRAP5b is claimed to be a specific marker of bone resorption [2-4]. Both osteopontin and bone sialoprotein are colocalized with TRAP5 in the resorption lacuna of osteoclasts and dephosphorylation of osteopontin impair its ability to promote adhesion as well as migration of osteoclasts in vitro [5].
MANUFACTURER Manufactured by BioVendor.
General Literature References
[1] Purification and N-terminal sequence of two tartrate-resistant acid phosphatases type-5 from the hairy cell leukemia spleen: J.J. Stepan, et al.; BBRC 165, 1027 (1989) Abstract
[2] Tartrate-resistant acid phosphatase 5b: a novel serum marker of bone resorption: J.M. Halleen, et al.; J. Bone Miner. Res 15, 1337 (2000) Abstract
[3] Tartrate-resistant acid phosphatase isoform 5b as serum marker for osteoclastic activity: A.J. Janckila, et al.; Clin. Chem. 47, 74 (2001) Abstract
[4] Clinical performance of immunoreactive tartrate-resistant acid phosphatase isoform 5b as a marker of bone resorption: R.A. Hannon, et al.; Bone 34, 187 (2001) Abstract
[5] TRACP as an osteopontin phosphatase: G. Andersson, et al.; J. Bone Miner. Res 18, 1912 (2003) Abstract
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
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