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ALX-151-001
Revised 25-Nov-04
β-Amyloid (1-43)
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
beta-Amyloid Peptides
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-001-PC01
0.1 mg*
120.00 USD
ALX-151-001-PC05
0.5 mg*
480.00 USD
Product Specification
SEQUENCE:
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-Thr-OH
FORMULA:
C
207
H
318
N
56
O
62
S
MW:
4615.3
QUANTITY:
*Sold as net peptide weight.
PURITY:
≥96%
APPEARANCE:
White lyophilized powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Specific Literature References
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease:
D. Goldgaber, et al.; Science
235
, 877 (1987)
Abstract
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor:
J. Kang, et al.; Nature
325
, 733 (1987)
Abstract
Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state:
C.J. Pike, et al.; J. Neurosci.
13
, 1676 (1993)
Abstract
Further Categories Containing This Product:
Peptides
ALX-151-002
Revised 07-Mar-05
β-Amyloid (1-42)
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
beta-Amyloid Peptides
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-002-PC05
0.5 mg*
350.00 USD
ALX-151-002-P001
1 mg*
620.00 USD
Product Specification
SEQUENCE:
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
FORMULA:
C
203
H
311
N
55
O
60
S
MW:
4514.1
QUANTITY:
*Sold as net peptide weight.
PURITY:
≥97%
APPEARANCE:
White lyophilized powder.
SOLUBILITY:
Soluble in 5% acetic acid.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Specific Literature References
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease:
D. Goldgaber, et al.; Science
235
, 877 (1987)
Abstract
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor:
J. Kang, et al.; Nature
325
, 733 (1987)
Abstract
A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease:
J. Murrell, et al.; Science
254
, 97 (1991)
Abstract
Solution structures of beta peptide and its constituent fragments: relation to amyloid deposition:
C.J. Barrow & M.G. Zagorski; Science
253
, 179 (1991)
Abstract
Further Categories Containing This Product:
Peptides
ALX-151-003
Revised 25-Nov-04
β-Amyloid (1-40)
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
beta-Amyloid Peptides
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-003-PC05
0.5 mg*
290.00 USD
ALX-151-003-P001
1 mg*
560.00 USD
Product Specification
SEQUENCE:
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH
FORMULA:
C
194
H
295
N
53
O
58
S
MW:
4329.9
QUANTITY:
*Sold as net peptide weight.
PURITY:
≥97%
APPEARANCE:
White lyophilized powder.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Specific Literature References
Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides:
B.A. Yankner, et al.; Science
250
, 279 (1990)
Abstract
The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease:
J.T. Jarrett, et al.; Biochemistry
32
, 4693 (1993)
Abstract
Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease:
H. Sticht, et al.; Eur. J. Biochem.
233
, 293 (1995)
Abstract
Further Categories Containing This Product:
Peptides
ALX-151-005
Revised 25-Nov-04
β-Amyloid (1-28)
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
beta-Amyloid Peptides
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-005-PC05
0.5 mg*
160.00 USD
ALX-151-005-P001
1 mg*
270.00 USD
Product Specification
SEQUENCE:
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH
FORMULA:
C
145
H
209
N
41
O
46
MW:
3262.5
QUANTITY:
*Sold as net peptide weight.
PURITY:
≥97%
APPEARANCE:
White lyophilized powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Specific Literature References
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor:
J. Kang, et al.; Nature
325
, 733 (1987)
Abstract
Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro:
D.A. Kirschner, et al.; PNAS
84
, 6953 (1987)
Abstract
Brain protein yields clues to Alzheimer's disease:
J.L. Marx; Science
243
, 1664 (1989)
Abstract
Is amyloid deposition in Alzheimer's disease preceded by an environment- induced double conformational transition?:
M. Hollosi, et al.; Pept. Res.
2
, 109 (1989)
Abstract
Amyloid beta protein enhances the survival of hippocampal neurons in vitro:
J.S. Whitson, et al.; Science
243
, 1488 (1989)
Abstract
Further Categories Containing This Product:
Peptides
ALX-151-007
Revised 14-Dec-04
[Gln11]-β-Amyloid (1-16)
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
beta-Amyloid Peptides
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-007-PC05
0.5 mg*
120.00 USD
ALX-151-007-P001
1 mg*
190.00 USD
Product Specification
SEQUENCE:
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Gln-Val-His-His-Gln-Lys-OH
FORMULA:
C
84
H
119
N
27
O
28
MW:
1955.0
CAS NUMBER:
133605-53-5
QUANTITY:
*Sold as net peptide weight.
PURITY:
≥97%
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Further Categories Containing This Product:
Peptides
ALX-151-008
Revised 23-Oct-07
β-Amyloid (25-35)
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
beta-Amyloid Peptides
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-008-P001
1 mg*
120.00 USD
ALX-151-008-P005
5 mg*
480.00 USD
Product Specification
SEQUENCE:
H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH
FORMULA:
C
45
H
81
N
13
O
14
S
MW:
1060.3
QUANTITY:
*Sold as net peptide weight.
PEPTIDE CONTENT:
70-90%
PURITY:
≥99% (HPLC)
APPEARANCE:
Lyophilized.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Specific Literature References
Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides:
B.A. Yankner, et al.; Science
250
, 279 (1990)
Abstract
Further Categories Containing This Product:
Peptides
ALX-151-009
Revised 13-Aug-02
β-Amyloid (10-20)
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
beta-Amyloid Peptides
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-009-P001
1 mg*
90.00 USD
ALX-151-009-P005
5 mg*
360.00 USD
Product Specification
SEQUENCE:
H-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-OH
FORMULA:
C
71
H
99
N
17
O
16
MW:
1446.7
QUANTITY:
*Sold as net peptide weight.
PURITY:
≥97%
APPEARANCE:
White lyophilized powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Specific Literature References
A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor:
K. Miyazaki, et al.; Nature
362
, 839 (1993)
Abstract
Further Categories Containing This Product:
Peptides
ALX-151-011
Revised 13-Jan-05
β-Amyloid/A4 Protein Precursor [APP] (328-332)
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
beta-Amyloid Peptides
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-011-P001
1 mg*
90.00 USD
ALX-151-011-P005
5 mg*
360.00 USD
Product Specification
SEQUENCE:
H-Arg-Glu-Arg-Met-Ser-OH
FORMULA:
C
25
H
47
N
11
O
9
S
MW:
677.8
QUANTITY:
*Sold as net peptide weight.
PURITY:
≥96%
APPEARANCE:
White lyophilized powder.
SOLUBILITY:
Soluble in TFA/water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Active domain of the amyloid β/A4 protein precursor (APP) that promotes fibroblast growth.
Product Specific Literature References
Amino acid sequence RERMS represents the active domain of amyloid beta/A4 protein precursor that promotes fibroblast growth:
H. Ninomiya, et al.; J. Cell. Biol.
121
, 879 (1993)
Abstract
Further Categories Containing This Product:
Peptides
ALX-151-013
Revised 05-Dec-06
Apamin
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
K+ Channel Blockers & Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-013-MC05
0.5 mg
150.00 USD
Product Specification
SEQUENCE:
H-Cys-Asn-Cys-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys-Ala-Arg-Arg-Cys-Gln-Gln-His-NH
2
(Disulfide bonds between Cys
1
-Cys
11
and Cys
3
-Cys
15
)
FORMULA:
C
131
H
131
N
31
O
24
S
4
MW:
2027.3
CAS NUMBER:
24345-16-2
MERCK INDEX:
14:
725
RTECS:
CD6899900
SOURCE/HOST:
Synthetic.
PURITY:
≥97% (HPLC)
APPEARANCE:
Lyophilized.
SOLUBILITY:
Soluble in 0.05M acetic acid; slightly soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Originally isolated from
Apis mellifera
. A small conductance Ca
2+
-activated K
+
channel blocker.
Product Specific Literature References
Toxins in the characterization of potassium channels:
N.A. Castle, et al.; TINS
12
, 59 (1989), (Review)
Abstract
Potassium channel toxins:
P.N. Strong; Pharmacol. Ther.
46
, 137 (1990)
Abstract
Further Categories Containing This Product:
Peptides
ALX-151-014
Revised 15-Dec-04
cAMP-dependent Protein Kinase Inhibitor (5-24)
SYNONYMS
PKA Inhibitor (5-24)
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-014-MC05
0.5 mg
90.00 USD
ALX-151-014-M001
1 mg
160.00 USD
Product Specification
SEQUENCE:
H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH
FORMULA:
C
94
H
148
N
32
O
31
MW:
2222.4
PURITY:
≥97%
APPEARANCE:
White to off-white powder.
FORMULATION:
Lyophilized.
SOLUBILITY:
Soluble in water or 5 % acetic acid.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Keep cool and dry.
Product Description
Potent inhibitor of cAMP-dependent protein kinase (PKA). The peptide corresponds to the active site of the skeletal muscle inhibitor protein.
Product Specific Literature References
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase:
H.-C. Cheng, et al.; J. Biol. Chem.
261
, 989 (1986)
Abstract
;
Full Text
Phosphorylation of Avena phytochrome in vitro as a probe of light- induced conformational changes:
Y.S. Wong, et al.; J. Biol. Chem.
261
, 12089 (1986)
Abstract
;
Full Text
Further Categories Containing This Product:
Peptides
ALX-151-016
Revised 17-Jan-05
cAMP-dependent Protein Kinase Inhibitor (5-22) amide
SYNONYMS
PKA Inhibitor (5-22) amide
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-151-016-MC05
0.5 mg
110.00 USD
ALX-151-016-M001
1 mg
180.00 USD
Product Specification
SEQUENCE:
H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH
2
FORMULA:
C
84
H
137
N
29
O
26
MW:
1969.2
PURITY:
≥97%
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Potent inhibitor of cAMP-dependent protein kinase (PKA).
Product Specific Literature References
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase:
H.-C. Cheng, et al.; J. Biol. Chem.
261
, 989 (1986)
Abstract
;
Full Text
Primary structural determinants essential for potent inhibition of cAMP- dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein:
D.B. Glass, et al.; J. Biol. Chem.
264
, 8802 (1989)
Abstract
;
Full Text
Further Categories Containing This Product:
Peptides
ALX-151-017
Revised 15-Dec-04
cAMP-dependent Protein Kinase Inhibitor (14-24) amide
SYNONYMS
PKA Inhibitor (14-24) amide
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKA Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
AL