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Monoclonal Antibodies
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ALX-802-004 Revised 18-Feb-08
Monoclonal Antibody to Acetylcholinesterase (ZR3)
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SYNONYMS anti-AChE MAb (ZR3)
PRODUCT LINE Neurobiology
PRODUCT CATEGORY Acetylcholine Esterase / Related Products
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ALX-802-004-R100   100 µl 379.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Rat
Others
CLONE: ZR3
ISOTYPE: Mouse IgG2b
PURITY DETAIL: Protein A-affinity purified.
FORMULATION: Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN: Purified rat brain AChE (acetylcholinesterase).
SPECIFICITY: Recognizes rat, guinea pig, rabbit and cat AChE. Does not cross-react with BChE (butyrylcholinesterase).
APPLICATION: Immunohistochemistry (1:1'000)
Immunoprecipitation
Not recommended for Western blot.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Monoclonal antibodies to rat brain acetylcholinesterase: comparative affinity for soluble and membrane-associated enzyme and for enzyme from different vertebrate species: Z. Rakonczay and S. Brimijoin; Neurochemistry 46, 280 (1986) Abstract
Selective destruction of preganglionic sympathetic nerves by antibodies to acetylcholinesterase: S. Brimijoin and V.A. Lennon; J. Neural Transm. Suppl. 34, 139 (1991) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION

Reacts with both the soluble and membrane-associated AChE. Immunohistochemical staining of AChE in rat brain results in staining of nerve fibers and terminals.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-009 Revised 31-Oct-06
Monoclonal Antibody to Ca2+/Calmodulin-dependent Protein Kinase II (rat) (α Subunit) (phosphorylated) (pThr286) (22B1)
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SYNONYMS anti-CAM Kinase II (rat) (α Subunit) (phosphorylated) (pThr286) MAb (22B1)
anti-CAMK2 (rat) (α Subunit) (phosphorylated) (pThr286) MAb (22B1)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinase Antibodies
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ALX-802-009-R100   100 µl 385.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
CLONE: 22B1
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 281-294 (M281HRQET(PSO3)VDCLKKFN294) of the α-subunit of mouse and rat CaM kinase II (Ca2+/Calmodulin-dependent Protein Kinase II) thiophosphorylated at (Thr286).
SPECIFICITY: Recognizes recombinant and native mouse and rat phosphorylated α-subunit of rat CaM kinase II.
APPLICATION: ELISA
Immunocytochemistry (1:100)
Immunoprecipitation
Western Blot (1:2'000)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Autophosphorylation of type II CaM kinase in hippocampal neurons: localization of phospho- and dephosphokinase with complementary phosphorylation site-specific antibodies: B.L. Patton, et al.; Mol. Biol. Cell 4, 159 (1993) Abstract
Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development: L.M. Esteban, et al.; Mol. Cell. Biol. 21, 1444 (2001) Abstract; Full Text
Cytoplasmic polyadenylation element binding protein-dependent protein synthesis is regulated by calcium/calmodulin-dependent protein kinase II: C.M. Atkins, et al.; J. Neurosci. 24, 5193 (2004) Abstract; Full Text
Further Categories Containing This Product:
Phospho-specific Antibodies • Monoclonal Antibodies
 
 
ALX-802-010 Revised 27-Jan-06
Monoclonal Antibody to Ca2+/Calmodulin-dependent Protein Kinase II (rat) (α Subunit) (6G9)
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SYNONYMS anti-CaM Kinase II (rat) (α Subunit) MAb (6G9)
anti-CAMK2 (rat) (α Subunit) MAb (6G9)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY CAM Kinase Antibodies
Ordering Information
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ALX-802-010-R100   100 µl 379.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Rat
CLONE: 6G9
ISOTYPE: Mouse IgG1
FORMULATION: Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN: Partially purified rat CaM kinase II (Ca2+/calmodulin-dependent protein kinase II).
SPECIFICITY: Recognizes recombinant and native phosphorylated and non-phosphorylated α-subunit of rat CaM kinase II.
APPLICATION: Immunocytochemistry (1:100)
Immunoprecipitation
Western Blot (1:2'000).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Regional distribution of type II Ca2+/calmodulin-dependent protein kinase in rat brain: N.E. Erondu & M.B. Kennedy.; J. Neurosci. 5, 3270 (1985) Abstract
Cytoplasmic polyadenylation element binding protein-dependent protein synthesis is regulated by calcium/calmodulin-dependent protein kinase II: C.M. Atkins, et al.; J. Neurosci. 24, 5193 (2004) Abstract; Full Text
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-020 Revised 01-Jul-08
Monoclonal Antibody to ART1 (human) (GUGU1-A3)
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SYNONYMS anti-ecto-ADP-ribosyltransferase 1 (human) MAb (GUGU1-A3)
anti-CD296 (human) MAb (GUGU1-A3)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases / Related Products
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ALX-802-020-L001   1 ml 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: GUGU1-A3
ISOTYPE: Rat IgG2b
FORMULATION: Liquid. Hybridoma supernatant containing 0.02% sodium azide.
IMMUNOGEN: Vector containing the cDNA of human ART1 (ecto-ADP-ribosyltransferase 1; CD296).
SPECIFICITY: Recognizes human ART1.
APPLICATION: Flow Cytometry (1:1-1:10)
Immunocytochemistry (1:1-1:10)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation: F. Koch-Nolte, et al.; Cell. Immunol. 236, 66 (2005) Abstract
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Di Girolamo; EMBO J. 22, 1953 (2003), (Review) Abstract; Full Text
Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling

: M. Seman, et al.; Curr. Med. Chem. 11, 857 (2004), (Review) Abstract
ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells: F. Koch-Nolte, et al.; Ann. Med. 38, 188 (2006), (Review) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-021 Revised 01-Jul-08
Monoclonal Antibody to ART2.1 (mouse) (GUGU2-B54)
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SYNONYMS anti-ecto-ADP-ribosyltransferase 2.1 (mouse) MAb (GUGU2-B54)
anti-ART2a (mouse) MAb (GUGU2-B54)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases / Related Products
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ALX-802-021-L001   1 ml 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE: GUGU2-B54
ISOTYPE: Rat IgG2a
FORMULATION: Liquid. Hybridoma supernatant containing 0.02% sodium azide.
IMMUNOGEN: Vector containing the cDNA of mouse ART2.1 (ecto-ADP-ribosyltransferase 2.1; ART2a).
SPECIFICITY: Recognizes mouse ART2.1.
APPLICATION: Flow Cytometry (1:1-1:10)
Immunocytochemistry (1:1-1:10)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation: F. Koch-Nolte, et al.; Cell. Immunol. 236, 66 (2005) Abstract
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Girolamo; EMBO J. 22, 1953 (2003), (Review) Abstract; Full Text
Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling: M. Seman, et al.; Curr. Med. Chem. 11, 857 (2004), (Review) Abstract
ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells: F. Koch-Nolte, et al.; Ann. Med. 38, 188 (2006), (Review) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-022 Revised 01-Jul-08
Monoclonal Antibody to ART2.2 (mouse) (NIKA-102)
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SYNONYMS anti-ecto-ADP-ribosyltransferase 2.2 (mouse) MAb (NIKA-102)
anti-ART2b (mouse) MAb (NIKA-102)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases / Related Products
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ALX-802-022-L001   1 ml 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE: NIKA-102
ISOTYPE: Rat IgG2a
FORMULATION: Liquid. Hybridoma supernatant containing 0.02% sodium azide.
IMMUNOGEN: Vector containing the cDNA of mouse ART2.2 (ecto-ADP-ribosyltransferase 2.2; ART2b).
SPECIFICITY: Recognizes mouse ART2.2.
APPLICATION: Flow Cytometry (1:1-1:10)
Immunocytochemistry (1:1-1:10)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
A new monoclonal antibody detects a developmentally regulated mouse ecto-ADP-ribosyltransferase on T cells: subset distribution, inbred strain variation, and modulation upon T cell activation: F. Koch-Nolte, et al.; J. Immunol. 163, 6014 (1999) Abstract; Full Text
Metalloprotease-mediated shedding of enzymatically active mouse ecto-ADP-ribosyltransferase ART2.2 upon T cell activation: S. Kahl, et al.; J. Immunol. 165, 4463 (2000) Abstract; Full Text
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Girolamo; EMBO J. 22, 1953 (2003), (Review) Abstract; Full Text
Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling: M. Seman, et al.; Curr. Med. Chem. 11, 857 (2004), (Review) Abstract
ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells: F. Koch-Nolte, et al.; Ann. Med. 38, 188 (2006), (Review) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-023 Revised 19-Oct-06
Monoclonal Antibody to ART3 (human) (GUGU3-A51)
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SYNONYMS anti-ecto-ADP-ribosyltransferase (human) MAb (GUGU3-A51)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases / Related Products
Ordering Information
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ALX-802-023-L001   1 ml 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: GUGU3-A51
ISOTYPE: Rat IgG2a
FORMULATION: Liquid. Hybridoma supernatant containing 0.02% sodium azide.
IMMUNOGEN: Vector containing the cDNA of human ART3 (ecto-ADP-ribosyltransferase 3).
SPECIFICITY: Recognizes human ART3.
APPLICATION: Flow Cytometry (1:1-1:10)
Immunocytochemistry (1:1-1:10)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation: F. Koch-Nolte, et al.; Cell. Immunol. 236, 66 (2005), (Review) Abstract
Expression of toxin-related human mono-ADP-ribosyltransferase 3 in human testes: M. Friedrich, et al.; Asian J. Androl. 8, 281 (2006) Abstract
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Di Girolamo; EMBO J. 22, 1953 (2003), (Review) Abstract; Full Text
Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling: M. Seman, et al.; Curr. Med. Chem. 11, 857 (2004), (Review) Abstract
ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells: F. Koch-Nolte, et al.; Ann. Med. 38, 188 (2006), (Review) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-024 Revised 19-Oct-06
Monoclonal Antibody to ART3 (mouse) (GUGU3-A34)
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SYNONYMS anti-ecto-ADP-ribosyltransferase 3 (mouse) MAb (GUGU3-A34)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases / Related Products
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ALX-802-024-L001   1 ml 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE: GUGU3-A34
ISOTYPE: Rat IgG2a
FORMULATION: Liquid. Hybridoma supernatant containing 0.02% sodium azide.
IMMUNOGEN: Vector containing the cDNA of mouse ART3 (ecto-ADP-ribosyltransferase 3).
SPECIFICITY: Recognizes mouse ART3.
APPLICATION: Flow Cytometry (1:1-1:10)
Immunocytochemistry (1:1-1:10)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation: F. Koch-Nolte, et al.; Cell. Immunol. 236, 66 (2005) Abstract
Expression of toxin-related human mono-ADP-ribosyltransferase 3 in human testes: M. Friedrich, et al.; Asian J. Androl. 8, 281 (2006) Abstract
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Di Girolamo; EMBO J. 22, 1953 (2003), (Review) Abstract; Full Text
Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling: M. Seman, et al.; Curr. Med. Chem. 11, 857 (2004), (Review) Abstract
ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells: F. Koch-Nolte; Ann. Med. 38, 188 (2006), (Review) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-025 Revised 01-Jul-08
Monoclonal Antibody to ART4 (human) (NONI-B4)
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SYNONYMS anti-ecto-ADP-ribosyltransferase 4 (human) MAb (NONI-B4)
anti-CD297 (human) MAb (NONI-B4)
anti-DO (human) MAb (NONI-B4)
anti-Dombrock Blood Group Carrier Molecule (human) MAb (NONI-B4)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases / Related Products
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ALX-802-025-L001   1 ml 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: NONI-B4
ISOTYPE: Rat IgG2a
FORMULATION: Liquid. Hybridoma supernatant containing 0.02% sodium azide.
IMMUNOGEN: Vector containing the cDNA of human ART4 (ecto-ADP-ribosyltransferase 4; CD297).
SPECIFICITY: Recognizes human ART4.
APPLICATION: Flow Cytometry (1:1-1:10)
Immunocytochemistry (1:1-1:10)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation: F. Koch-Nolte; Cell. Immunol. 236, 66 (2005) Abstract
A panel of monoclonal antibodies recognizing GPI-anchored ADP-ribosyltransferase ART4, the carrier of the Dombrock blood group antigens: I. Parusel, et al.; Cell Immunol. 236, 59 (2005) Abstract
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Di Girolamo; EMBO J. 22, 1953 (2003), (Review) Abstract; Full Text
Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling: M. Seman, et al.; Curr. Med. Chem. 11, 857 (2004), (Review) Abstract
Complexities of the Dombrock blood group system revealed: M.E. Reid; Transfusion 45, 92S (2005) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-026 Revised 01-Jul-08
Monoclonal Antibody to ART4 (mouse) (GUGU4-A53)
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SYNONYMS anti-ecto-ADP-ribosyltransferase 4 (mouse) MAb (GUGU4-A53)
anti-CD297 (mouse) MAb (GUGU4-A53)
anti-DO (mouse) MAb (GUGU4-A53)
anti-Dombrock Blood Group Carrier Molecule (mouse) (GUGU4-A53)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY Mono(ADP-ribosyl)transferases / Related Products
Ordering Information
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ALX-802-026-L001   1 ml 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE: GUGU4-A53
ISOTYPE: Rat IgG2a
FORMULATION: Liquid. Hybridoma supernatant containing 0.02% sodium azide.
IMMUNOGEN: Vector containing the cDNA of mouse ART4 (ecto-ADP-ribosyltransferase 4; CD297).
SPECIFICITY: Recognizes mouse ART4.
APPLICATION: Flow Cytometry (1:1-1:10)
Immunocytochemistry (1:1-1:10)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
Product Specific Literature References
Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation: F. Koch-Nolte, et al.; Cell. Immunol. 236, 66 (2005) Abstract
General Literature References
Functional aspects of protein mono-ADP-ribosylation: D. Corda & M. Di Girolamo; EMBO J. 1953, 22 (2003), (Review) Abstract; Full Text
Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling: M. Seman, et al.; Curr. Med. Chem. 11, 857 (2004), (Review) Abstract
Complexities of the Dombrock blood group system revealed: M.E. Reid; Transfusion 45, 92S (2005), (Review) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-802-027 Revised 07-Jun-07
Monoclonal Antibody to Purinergic Receptor P2X7 (mouse) (HANO43)
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SYNONYMS anti-P2X Purinoceptor 7 (mouse) MAb (HANO43)
anti-P2RX7 (mouse) MAb (HANO43)
PRODUCT LINE Neurobiology
PRODUCT CATEGORY P2X Purinergic Receptors / Related Products
Ordering Information
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ALX-802-027-L001   1 ml 330.00 USD