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Items 206 of 206
ALX-804-148
Revised 31-Oct-06
Monoclonal Antibody to APRIL (human) (Aprily-1)
SYNONYMS
anti-A-Proliferation-inducing Ligand (human) MAb (Aprily-1)
anti-TNFSF 13 (human) MAb (Aprily-1)
anti-CD256 (human) MAb (Aprily-1)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
APRIL
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-148-C100
100 µg
320.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
Aprily-1
ISOTYPE:
Mouse IgG1
SOURCE/HOST:
Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION:
1mg/ml
PURITY:
95% (SDS-PAGE)
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Recombinant human APRIL (aa 93-233).
SPECIFICITY:
Recognizes human APRIL. Does not cross-react with mouse APRIL.
APPLICATION:
Flow Cytometry
Immunoprecipitation
Western Blot (excellent)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored as recommended.
HANDLING:
Avoid freeze/thaw cycles.
POSITIVE CONTROL:
For Positive Control (Western blot) see Prod. No.
ALX-840-607
.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
BAFF production by antigen-presenting cells provides T cell co-stimulation
:
Int. Immunol.; B. Huard, et al.
16
, 467 (2004)
Abstract
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
General Literature References
BAFF and APRIL: A Tutorial on B Cell Survival
:
F. Mackay, et al.; Annu. Rev. Immunol. (2002)
Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-804-844
Revised 20-Jun-08
Monoclonal Antibody to APRIL (human) (Aprily-2)
SYNONYMS
anti-A-Proliferation-inducing Ligand (human) MAb (Aprily-2)
anti-TNFSF 13 (human) MAb (Aprily-2)
anti-CD256 (human) MAb (Aprily-2)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
APRIL
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-844-C100
100 µg
320.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
Aprily-2
ISOTYPE:
Mouse IgG1
SOURCE/HOST:
Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION:
1mg/ml
PURITY:
95% (SDS-PAGE)
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Recombinant human APRIL (aa 93-233).
SPECIFICITY:
Recognizes human APRIL.
APPLICATION:
Immunohistochemistry (paraffin sections (1:500))
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored as recommended.
HANDLING:
Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
The source of APRIL up-regulation in human solid tumor lesions:
P. Mhawech-Fauceglia, et al.; J. Leukoc. Biol.
80
, 697 (2006)
Abstract
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
General Literature References
BAFF and APRIL: A Tutorial on B Cell Survival
:
F. Mackay, et al.; Annu. Rev. Immunol. (2002)
Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-804-801
Revised 20-Oct-08
Monoclonal Antibody to APRIL (human) (Aprily-5)
SYNONYMS
anti-A-Proliferation-inducing Ligand (human) MAb (Aprily-5)
anti-TNFSF 13 (human) MAb (Aprily-5)
anti-CD256 (human) MAb (Aprily-5)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
APRIL
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-801-C100
100 µg
320.00 USD
ALX-804-801B-C100
Biotin
100 µg
390.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
Aprily-5
ISOTYPE:
Mouse IgG1
SOURCE/HOST:
Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION:
1mg/ml
PURITY:
95% (SDS-PAGE)
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Recombinant human APRIL (aa 93-233).
SPECIFICITY:
Recognizes full-length and cleaved human APRIL. Does not cross-react with mouse APRIL.
APPLICATION:
ELISA (detection)
Immunoprecipitation
Western Blot (excellent)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:
For long term storage keep unconjugated antibody at -20°C. Avoid freeze/thaw cycles. Keep conjugated formats at +4°C. Do not freeze. Protect from light.
POSITIVE CONTROL:
For Positive Control (Western blot) see Prod. No.
ALX-840-607
.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-804-149
Revised 31-Mar-08
Monoclonal Antibody to APRIL (human) (Aprily-8)
SYNONYMS
anti-A-Proliferation-inducing Ligand (human) MAb (Aprily-8)
anti-TNFSF 13 (human) MAb (Aprily-8)
anti-CD256 (human) MAb (Aprily-8)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
APRIL
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-149-C100
100 µg
320.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
Aprily-8
ISOTYPE:
Mouse IgG1
SOURCE/HOST:
Purified from concentrated hybridoma tissue supernatant.
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE).
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Recombinant human APRIL (aa 93-233).
SPECIFICITY:
Recognizes human APRIL and TWE-PRIL. Does not cross-react with mouse APRIL and TWE-PRIL.
APPLICATION:
Flow Cytometry
Immunocytochemistry (excellent)
Immunohistochemistry (paraffin sections)
Immunoprecipitation
Western Blot (excellent)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least one year after receipt when stored at -20°C.
HANDLING:
Avoid freeze/thaw cycles.
POSITIVE CONTROL:
For Positive Control (Western blot) see Prod. No.
ALX-840-607
.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Expression of TNF-superfamily members BAFF and APRIL in breast cancer: Immunohistochemical study in 52 invasive ductal breast carcinomas:
V. Pelekanou, et al.; BMC Cancer
8
, 76 (2008)
Abstract
;
Full Text
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
General Literature References
BAFF and APRIL: A Tutorial on B Cell Survival
:
F. Mackay, et al.; Annu. Rev. Immunol. (2002)
Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-804-141
Revised 18-Sep-06
Monoclonal Antibody to APRIL (Sacha-1)
SYNONYMS
anti-A-Proliferation-inducing Ligand MAb (Sacha-1)
anti-TNFSF 13 MAb (Sacha-1)
anti-CD256 MAb (Sacha-1)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
APRIL
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-141-C100
100 µg
290.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
CLONE:
Sacha-1
ISOTYPE:
Rat IgG2a
SOURCE/HOST:
Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE)
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Recombinant human APRIL (aa 105-250) fused to human ACRP30
headless
(aa 16-108) (Prod. No.
ALX-522-035
).
SPECIFICITY:
Recognizes human and mouse APRIL.
APPLICATION:
Flow Cytometry (excellent for mouse APRIL, also stains human APRIL)
Immunocytochemistry
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
USE/STABILITY:
Stable for at least 6 months after receipt when stored at +4°C undiluted.
HANDLING:
Do not freeze/thaw.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-804-804
Revised 13-Mar-07
Monoclonal Antibody to APRIL (Sacha-2)
SYNONYMS
anti-A-Proliferation-inducing Ligand MAb (Sacha-2)
anti-TNFSF 13 MAb (Sacha-2)
anti-CD256 MAb (Sacha-2)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
APRIL
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-804-C100
100 µg
320.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
CLONE:
Sacha-2
ISOTYPE:
Rat IgG2a
SOURCE/HOST:
Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE)
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Recombinant human APRIL (aa 105-250) fused to human ACRP30
headless
(aa 16-108) (Prod. No.
ALX-522-035
).
SPECIFICITY:
Recognizes human and mouse APRIL.
APPLICATION:
ELISA (capture)
Flow Cytometry
Immunocytochemistry
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
USE/STABILITY:
Stable for at least 6 months after receipt when stored at +4°C undiluted.
HANDLING:
Do not freeze/thaw.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-804-131
Revised 31-Mar-08
Monoclonal Antibody to BAFF (Buffy-2)
SYNONYMS
anti-BLyS MAb (Buffy-2)
anti-TALL-1 MAb (Buffy-2)
anti-THANK MAb (Buffy-2)
anti-zTNF4 MAb (Buffy-2)
anti-TNFSF 13B/20 MAb (Buffy-2)
anti-CD257 MAb (Buffy-2)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
BAFF
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-131-C100
100 µg
360.00 USD
ALX-804-131F-T100
FITC
100 tests
380.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
CLONE:
Buffy-2
ISOTYPE:
Rat IgM
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE)
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Recombinant human soluble BAFF (aa 83-285) (Prod. No.
ALX-522-025
).
SPECIFICITY:
Recognizes membrane-bound and soluble human and mouse (weak) BAFF.
APPLICATION:
Buffy-2
:
Flow Cytometry (see [3])
Immunohistochemistry (frozen sections, paraffin sections)
Western Blot
Buffy-2-FITC
:
Flow Cytometry (see [3])
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
USE/STABILITY:
Stable for at least 6 months after receipt when stored as recommended.
HANDLING:
Do not freeze/thaw.
POSITIVE CONTROL:
For Positive Control (Western blot) see Prod. No.
ALX-840-605
.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
[1]
Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome
:
J. Groom, et al.; J. Clin. Invest.
109
, 59 (2002)
Abstract
;
Full Text
[2]
Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival
:
A. J. Novak, et al.; Blood
103
, 689 (2004)
Abstract
[3]
Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL
:
B. He, et al.; J. Immunol.
172
, 3268 (2004)
Abstract
;
Full Text
[4]
BAFF production by antigen-presenting cells provides T cell co-stimulation
:
B. Huard, et al.; Int. Immunol.
16
, 467 (2004)
Abstract
[5]
Expression of BLyS and its Receptors in B-Cell Non-Hodgkin Lymphoma: Correlation with Disease Activity and Patient Outcome
:
A.J. Novak, et al.; Blood
104
, 2247 (2004)
Abstract
[6]
Association between circulating levels of the novel TNF family members APRIL and BAFF and lymphoid organization in primary Sjogren’s syndrome:
M.V. Jonsson, et al.; J. Clin. Immunol.
25
, 189 (2005)
Abstract
[7]
Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt’s lymphoma:
C.A. Ogden, et al.; J. Immunol.
174
, 3015 (2005)
Abstract
;
Full Text
[8]
In vitro and in vivo activation induces BAFF and APRIL expression in B cells:
V.T. Chu, et al.; J. Immunol.
179
, 5947 (2007)
Abstract
Expression of TNF-superfamily members BAFF and APRIL in breast cancer: Immunohistochemical study in 52 invasive ductal breast carcinomas:
V. Pelekanou, et al.; BMC Cancer
8
, 76 (2008)
Abstract
;
Full Text
General Information
BACKGROUND/TECHNICAL INFORMATION
FITC-conjugated antibody:
1 test means: 1µl of a 0.1mg/ml stock solution were used to stain 200'000 cells in a sample volume of 50µl.
MANUFACTURER
Manufactured by Apotech Corporation.
General Literature References
Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
:
F. Mackay, et al.; J. Exp. Med.
190
, 1697 (1999)
Abstract
;
Full Text
BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator
:
P.A. Moore, et al.; Science
285
, 260 (1999)
Abstract
Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-kB, and c-Jun NH2-terminal kinase
:
A. Mukhopadhyay, et al.; J. Biol. Chem.
274
, 15978 (1999)
Abstract
;
Full Text
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth
:
P. Schneider, et al.; J. Exp. Med.
189
, 1747 (1999)
Abstract
;
Full Text
TALL-1 is a novel member of the TNF family that is down-regulated by mitogens
:
H.B. Shu, et al.; J. Leukoc. Biol.
65
, 680 (1999)
Abstract
Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
:
S.D. Khare, et al.; PNAS
97
, 3370 (2000)
Abstract
;
Full Text
Related Products
ALX-522-025
BAFF, Soluble (human) (recombinant)
ALX-840-605
Positive Control (Cell Lysate) for Antibodies to BAFF (human)
ALX-211-054
Polyclonal Antibody to Rat IgM (Rat Ig adsorbed) (FITC)
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-804-159
Revised 30-Jun-05
Monoclonal Antibody to BAFF (human) (4D3)
SYNONYMS
anti-BLyS (human) MAb (4D3)
anti-TALL-1 (human) MAb (4D3)
anti-THANK (human) MAb (4D3)
anti-zTNF4 (human) MAb (4D3)
anti-TNFSF 13B/20 (human) MAb (4D3)
anti-CD257 (human) MAb (4D3)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
BAFF
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-159-C100
100 µg
360.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
4D3
ISOTYPE:
Mouse IgG1
SOURCE/HOST:
Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION:
1mg/ml
PURITY:
95% (SDS-PAGE)
FORMULATION:
Liquid. In PBS.
IMMUNOGEN:
Recombinant human BAFF.
SPECIFICITY:
Recognizes human BAFF.
APPLICATION:
Flow Cytometry
Immunohistochemistry (frozen sections)
Functional Application (inhibition)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:
Avoid freeze/thaw cycles.
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-804-147
Revised 08-Apr-05
Monoclonal Antibody to BAFF (human) (Buffy-XI)
SYNONYMS
anti-BLyS (human) MAb (Buffy-XI)
anti-TALL-1 (human) MAb (Buffy-XI)
anti-THANK (human) MAb (Buffy-XI)
anti-zTNF4 (human) MAb (Buffy-XI)
anti-TNFSF 13B/20 (human) MAb (Buffy-XI)
anti-CD257 (human) MAb (Buffy-11)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
BAFF
