• Home
  • Sitemap
  • Help
  • Technical Support
  • Contact
Inositols & Inositolphosphates / Related Products
You are here: Product Lines > Bone Metabolism > Inositols & Inositolphosphates / Related Products
Toolbar - View Selection
 
 Items 1-20 of 56 Page 1 of 3 Select Page: 1 2 3  >>  
ALX-210-115/1 Revised 23-Oct-08
Polyclonal Antibody to Inositol 1,4,5-trisphosphate Receptor (Type-I)
Add to Clipboard
SYNONYMS anti-IP3 Receptor (Type-I) PAb
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-115/1-R100   100 µl 379.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 1829-1848(N1829KKKDD
EVDRDAPSRKKAKE1848) of the cytoplasmic C-terminal domain of human IP3R-I (inositol 1,4,5-trisphosphate receptor (type-I)). This sequence is completely conserved in mouse and rat IP3R-I.
SPECIFICITY: Recognizes mouse and rat IP3R-I. Detects a band of ~240-260kDa by Western blot.
APPLICATION: Western Blot
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
BLOCKING PEPTIDE: For Blocking Peptide see Prod. No. ALX-159-003.
Related Products
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-224 Revised 10-Mar-06
Polyclonal Antibody to Inositol 1,4,5-trisphosphate Receptor (Type-II)
Add to Clipboard
SYNONYMS anti-IP3 Receptor (Type-II) PAb
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-224-R100   100 µl 379.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Epitope-affinity purified IgG.
FORMULATION: Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 317-334 (E317LNPDYRDAQNEGKTVRD334) of the cytoplasmic N-terminal domain of rat IP3R-II (inositol 1,4,5-trisphosphate receptor (type-II)).
SPECIFICITY: Recognizes mouse and rat IP3R-II.
APPLICATION: Immunohistochemistry (frozen sections (1:100))
Note: Not recommended for Western blot.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
BLOCKING PEPTIDE: For Blocking Peptide see Prod. No. ALX-159-004.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice: K.D. Garcia, et al.; Am. J. Physiol. Cell Physiol. 287, C1048 (2004) Abstract; Full Text
Related Products
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-289 Revised 15-Mar-07
Polyclonal Antibody to Inositol Hexakisphosphate Kinase (rat)
Add to Clipboard
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-289-C100   100 µg 379.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Rat
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml
PURITY DETAIL: Epitope-affinity purified IgG.
FORMULATION: Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 216-233 of human IP6 kinase (inositol hexakisphosphate kinase).
SPECIFICITY: Recognizes rat IP6 kinase. Detects a band of ~50kDa by Western blot.
APPLICATION: Western Blot (0.5µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
BLOCKING PEPTIDE: For Blocking Peptide see Prod. No. ALX-159-005.
Product Images
Please click on thumbnails to enlarge.
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-745 Revised 19-Mar-07
Polyclonal Antibody to Phosphatidylinositol-4-phosphate 5-kinase-Iγ
Add to Clipboard
SYNONYMS anti-PIP5K-Iγ PAb
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-745-C200   200 µg 340.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 2mg/ml
PURITY DETAIL: Epitope-affinity purified IgG.
FORMULATION: Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 622-641 (A622SDEEDAPSTDIYFPTDERS641) of C-terminal mouse PIP5K-Iγ (phosphatidylinositol-4-phosphate 5-kinase-Iγ).
SPECIFICITY: Recognizes two alternative splicing forms (87 and 90kDa) of human and mouse PIP5K-Iγ.
APPLICATION: Immunocytochemistry (1:300)
Immunohistochemistry (paraffin sections)
Western Blot (1:1'000)
QUALITY CONTROL: Western blot on mouse spleen and mouse brain lysates.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap. After opening, prepare aliquots and store at -20°C.
BLOCKING PEPTIDE: For Blocking Peptide see Prod. No. ALX-165-032.
Product Specific Literature References
Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family: H. Ishihara, et al.; J. Biol. Chem. 273, 8741 (1998) Abstract; Full Text
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-954 Revised 22-Jul-08
Polyclonal Antibody to WIPI-1 (human) (AT129)
Add to Clipboard
SYNONYMS anti-WD Repeat Domain Phosphoinositide-interacting Protein 1 (human) PAb (AT129)
anti-WD40 Repeat Protein Interacting with Phosphoinositides of 49kDa (human) PAb (AT129)
anti-WIPI 49kDa (human) PAb (AT129)
anti-Atg18 Protein Homolog (human) PAb (AT129)
PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY Autophagy-related Proteins [APG; ATG] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-954-C050   50 µg 310.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Others
SOURCE/HOST: From rabbit.
CONCENTRATION: 0.5mg/ml
PURITY: Epitope-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa of C-terminal human WIPI-1.
SPECIFICITY: Recognizes human WIPI-1.
APPLICATION: Western blot (1:1’000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
General Information

WIPI-1 (WD-repeat protein interacting with phosphoinosides) is highly expressed in a variety of tumors. It interacts with phosphatidylinositol-3-P and this interaction is required for recruitment to membranes. WIPI-1 contains the signature motif LXXLL for nuclear receptor association and it binds to estrogen and androgen receptors in vitro. The WIPI-1 homolog in S. cerevisiae (Atg18) plays a role in autophagy. WIPI-1 accumulates in multi-membrane structures under autophagic conditions and it co-localizes with LC3.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy: T. Proikas-Cezanne, et al.; FEBS Lett. 581, 3396 (2007) Abstract
Related Products
Further Categories Containing This Product:
Estrogen & Estrogen Receptors / Related Products • Androgens & Androgen Receptors / Related Products • Polyclonal Antibodies • Inositols & Inositolphosphates / Related Products
 
 
ALX-210-955 Revised 11-Mar-08
Polyclonal Antibody to WIPI-1 (AT130)
Add to Clipboard
SYNONYMS anti-WD Repeat Domain Phosphoinositide-interacting Protein 1 PAb (AT130)
anti-WD40 Repeat Protein Interacting with Phosphoinositides of 49kDa PAb (AT130)
anti-WIPI 49kDa PAb (AT130)
anti-Atg18 Protein Homolog PAb (AT130)
PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY Autophagy-related Proteins [APG; ATG] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-955-C100   100 µg 350.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Others
SOURCE/HOST: From rabbit.
CONCENTRATION: 0.5mg/ml
PURITY: Epitope-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa in the middle of human WIPI-1.
SPECIFICITY: Recognizes human and mouse WIPI-1.
APPLICATION: Western blot (1:1’000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
General Information
WIPI-1 (WD-repeat protein interacting with phosphoinosides) is highly expressed in a variety of tumors. It interacts with phosphatidylinositol-3-P and this interaction is required for recruitment to membranes. WIPI-1 contains the signature motif LXXLL for nuclear receptor association and it binds to estrogen and androgen receptors in vitro. The WIPI-1 homolog in S. cerevisiae (Atg18) plays a role in autophagy. WIPI-1 accumulates in multi-membrane structures under autophagic conditions and it co-localizes with LC3.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy: T. Proikas-Cezanne, et al.; FEBS Lett. 581, 3396 (2007) Abstract
Related Products
Further Categories Containing This Product:
Estrogen & Estrogen Receptors / Related Products • Androgens & Androgen Receptors / Related Products • Polyclonal Antibodies • Inositols & Inositolphosphates / Related Products
 
 
ALX-307-001 Revised 18-Feb-08
L-Quebrachitol
Add to Clipboard
SYNONYMS 1L-2-O-Methyl-chiro-inositol
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Natural Products - Other Signal Transduction Pathway Modulators
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-001-G001   1 g 40.00 USD Add To Cart
Product Specification
FORMULA: C7H14O6
MW: 194.2
CAS NUMBER: 642-38-6
SOURCE/HOST: Isolated from rubber tree.
PURITY: ≥98%
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in DMSO, dimethyl formamide or water.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C

Product Description
Key starting material for the synthesis of optically active inositol phosphates.
Product Specific Literature References
Synthesis of 1D-3-deoxy-, 1D-2,3-dideoxy-, and 1D-2,3,6-trideoxy-myo-inositol 1,4,5-trisphosphate from quebrachitol, their binding affinities, and calcium release activity: A.P. Kozikowski, et al.; JACS 115, 4429 (1993)
Synthesis and Biological Activity of the D-3-Deoxy-3-fluoro and D-3-Chloro-3-deoxy Analogs of Phosphatidylinositol: A.P. Kozikowski, et al.; J. Org. Chem. 59, 963 (1994)
Quebrachitol: A Versatile Building Block in the Construction of Naturally
Occurring Bioactive Materials: J.J. Kiddle; Chem. Rev. 95, 2189 (1995), (Review) Abstract
A versatile approach to PI(3,4)P2, PI(4,5)P2, and PI(3,4,5)P3 from L-(-)-quebrachitol: L. Qiao, et al.; Org. Lett. 2, 115 (2000) Abstract
Further Categories Containing This Product:
Chiral Compounds (Organic) • Chemical Synthesis - Reagents & Intermediates • Inositols & Inositolphosphates / Related Products
 
 
ALX-307-002 Revised 24-Feb-05
1-D-3-Deoxy-phosphatidylinositol
Add to Clipboard
SYNONYMS DPI
3-Deoxy-D-myo-inositol 1-[(R)-2,3-bis(hexa-
decanoyloxy)propyl hydrogenphosphate]
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-002-C100   100 µg 30.00 USD Add To Cart
ALX-307-002-M001   1 mg 150.00 USD Add To Cart
Product Specification
FORMULA: C41H79O12P
MW: 795.0
PURITY: ≥98%
APPEARANCE: Off-white amorphous solid.
SOLUBILITY: Solube in DMSO or 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C

Product Description
Antimetabolite of phosphatidylinositol-3-phosphate. Inhibitor of cancer cell colony formation.
Product Specific Literature References
Synthesis and biology of 1D-3-deoxyphosphatidylinositol: a putative antimetabolite of phosphatidylinositol-3-phosphate and an inhibitor of cancer cell colony formation: A.P. Kozikowski, et al.; J. Med. Chem. 38, 1053 (1995) Abstract
Further Categories Containing This Product:
Chemopreventive Agents Other Products
 
 
ALX-307-003 Revised 19-Aug-08
myo-Inositol
Add to Clipboard
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-003-G025   25 g 18.00 USD Add To Cart
Product Specification
FORMULA: C6H12O6
MW: 180.2
CAS NUMBER: 87-89-8
MERCK INDEX: 14: 4978
RTECS: NM7520800
PURITY: ≥98%
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in water; slightly soluble in 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +20°C
IDENTITY: Identity determined by IR.

 
 
ALX-307-004 Revised 04-Apr-07
scyllo-Inositol
Add to Clipboard
SYNONYMS Scyllitol
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-004-M005   5 mg 45.00 USD Add To Cart
ALX-307-004-M025   25 mg 180.00 USD Add To Cart
Product Specification
FORMULA: C6H12O6
MW: 180.2
CAS NUMBER: 488-59-5
PURITY: ≥98%
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water (50mg/ml).
SHIPPING: AMBIENT
LONG TERM STORAGE: +20°C

Product Description
Naturally occuring isomer of myo-inositol (Prod. No. ALX-307-003).
Product Specific Literature References
In vivo conversion of [3H]myoinositol to [3H]chiroinositol in rat tissues: Y. Pak, et al.; J. Biol. Chem. 267, 16904 (1992) Abstract; Full Text
Phosphoinositide metabolism in the developing conceptus. Effects of hyperglycemia and scyllo-inositol in rat embryo culture: P.J. Strieleman, et al.; Diabetes 41, 989 (1992) Abstract
 
 
ALX-307-005 Revised 21-Nov-08
D-myo-Inositol 1,3,4,5-tetrakisphosphate . tetrapotassium salt
Add to Clipboard
SYNONYMS Ins(1,3,4,5)P4 . 4K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-005-C100   100 µg 180.00 USD Add To Cart
ALX-307-005-M001