ALEXIS Biochemicals: CD14 (mouse) (recombinant) (His)

ALX-201-134

Revised 20-Feb-07

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-201-134-C010		10 µg	370.00 USD

Product Specification

MW:	~50kDa
SOURCE/HOST:	Produced in CHO cells.
CONCENTRATION:	1mg/ml after reconstitution.
PURITY DETAIL:	His-tag-affinity purified.
FORMULATION:	Lyophilized from PBS, pH 7.2.
ENDOTOXIN CONTENT:	<0.00015EU/µg protein (LAL test; Chromogenix).
RECONSTITUTION:	Reconstitute with 10µl distilled water.
BIOLOGICAL ACTIVITY:	Inhibits binding of LPS to CD14. Up to 5µg/ml mouse CD14 inhibit binding of FITC-LPS (0.5µg/ml) to mouse CD14⁺ CHO transfectants (FACS).
SHIPPING:	SHIPPED ON DRY ICE
LONG TERM STORAGE:	-80°C
HANDLING:	Avoid freeze/thaw cycles.

Product Specific Literature References

Monocytes can phagocytose Gram-negative bacteria by a CD14-dependent mechanism: U. Grunwald, et al.; J. Immunol. 157, 4119 (1996) Abstract

General Information

The myeloid differentiation antigen CD14 acts as the major receptor for bacterial LPS. The dominant form of the recombinant wildtype CD14 ist the 50kDa protein.
MANUFACTURER	Manufactured by Biometec.

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