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Clusterin/Related Products
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AG-CC06H2 Revised 11-Jan-08
Clusterin (human) Competitive ELISA Kit
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SYNONYMS TRPM-2 (human) Competitive ELISA Kit
Apolipoprotein J (human) Competitive ELISA Kit
APO-J (human) Competitive ELISA Kit
CLI (human) Competitive ELISA Kit
CLU (human) Competitive ELISA Kit
SGP-2 (human) Competitive ELISA Kit
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY Clusterin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-CC06H2EK-KI01   96 wells 550.00 USD Add To Cart
AG-CC06H2PP-KI01 Penta Plex 5x96 wells 1'870.00 USD Add To Cart
AG-CC06H2TP-KI01 Twin Plex 2x96 wells 890.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY: 1ng/ml
APPLICATION: For the quantitative determination of clusterin in human serum, plasma or cell culture supernatant.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-201-355 Revised 18-Mar-08
Clusterin (nuclear form) (human) (recombinant) (His)
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SYNONYMS TRPM-2 (nuclear form) (human) (recombinant) (His)
Apolipoprotein J (nuclear form) (human) (recombinant) (His)
APO-J (nuclear form) (human) (recombinant) (His)
CLI (nuclear form) (human) (recombinant) (His)
CLU (nuclear form) (human) (recombinant) (His)
SGP-2 (nuclear form) (human) (recombinant) (His)
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY Clusterin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-355-C050   50 µg 395.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in E. coli. Mature human nuclear clusterin (aa 23-449) is fused at the C-terminus to a His-tag.
CONCENTRATION: 1mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM sodium chloride.
ENDOTOXIN CONTENT: <1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Images
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General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link P10909: Clusterin (human) [Precursor]
MANUFACTURER Manufactured by AdipoGen, Inc.
General Literature References
Inhibition of post-ischemic brain injury by clusterin overexpression: P. Wehrli, et al.; Nat. Med. 7, 977 (2001) Abstract
Clusterin/apolipoprotein J in human aging and cancer: I.P. Trougakos and E.S. Gonos; Int. J. Biochem. Cell Biol. 34, 1430 (2002) Abstract
Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer: B. Shannan, et al.; Cell Death Differ. 13, 12 (2006) Abstract
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
ALX-201-365 Revised 18-Mar-08
Clusterin (nuclear form) (mouse) (recombinant) (His)
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SYNONYMS TRPM-2 (nuclear form) (mouse) (recombinant) (His)
Apolipoprotein J (nuclear form) (mouse) (recombinant) (His)
APO-J (nuclear form) (mouse) (recombinant) (His)
CLI (nuclear form) (mouse) (recombinant) (His)
CLU (nuclear form) (mouse) (recombinant) (His)
SGP-2 (nuclear form) (mouse) (recombinant) (His)
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY Clusterin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-365-C050   50 µg 395.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in E. coli. Mature mouse nuclear clusterin (aa 22-448) is fused at the C-terminus to a His-tag.
CONCENTRATION: 1mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM sodium chloride.
ENDOTOXIN CONTENT: <1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q549A5: Clusterin (mouse) [Precursor]
MANUFACTURER Manufactured by AdipoGen, Inc.
General Literature References
Inhibition of post-ischemic brain injury by clusterin overexpression: P. Wehrli, et al.; Nat. Med. 7, 977 (2001) Abstract
Clusterin/apolipoprotein J in human aging and cancer: I.P. Trougakos and E.S. Gonos; Int. J. Biochem. Cell Biol. 34, 1430 (2002) Abstract
Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer: B. Shannan, et al.; Cell Death Differ. 13, 12 (2006) Abstract
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
ALX-201-358 Revised 18-Mar-08
Clusterin (secretory form) (human) (recombinant)
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SYNONYMS TRPM-2 (secretory form) (human) (recombinant)
Apolipoprotein J (secretory form) (human) (recombinant)
APO-J (secretory form) (human) (recombinant)
CLI (secretory form) (human) (recombinant)
CLU (secretory form) (human) (recombinant)
SGP-2 (secretory form) (human) (recombinant)
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY Clusterin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-358-C010   10 µg 230.00 USD Add To Cart
ALX-201-358-C050   50 µg 480.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. The signal peptide sequence and the mature human secretory clusterin (aa 1-449) is fused at the C-terminus to a FLAG®-tag.
CONCENTRATION: 0.5mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2 µm-filtered solution in PBS, pH 7.2.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link P10909: Clusterin (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
ALX-804-126 Revised 04-May-07
Monoclonal Antibody to Clusterin (human) (CLI-9)
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SYNONYMS anti-TRPM-2 (human) MAb (CLI-9)
anti-Apolipoprotein J (human) MAb (CLI-9)
anti-APO-J (human) MAb (CLI-9)
anti-CLI (human) MAb (CLI-9)
anti-CLU (human) MAb (CLI-9)
anti-SGP-2 (human) MAb (CLI-9)
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY Clusterin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-126-C100   100 µg 280.00 USD Add To Cart
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Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: CLI-9
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Purified human clusterin (TRPM-2).
SPECIFICITY: Recognizes human clusterin.
APPLICATION: Immunocytochemistry
Immunohistochemistry (frozen sections, paraffin sections)
Immunoprecipitation
Western Blot (1:2’000)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at +4°C undiluted.
HANDLING: Do not freeze/thaw.
Product Specific Literature References
Large-scale serial analysis of gene expression reveals genes differentially expressed in ovarian cancer  : C. D. Hough, et al.; Cancer Res. 60, 6281 (2000) Abstract
Clusterin-mediated apoptosis is regulated by adenomatous polyposis coli and is p21 dependent but p53 independent: T. Chen, et al.; Cancer Res. 64, 7412 (2004) Abstract; Full Text
General Information
Clusterin (SGP-2/sulfated glycoprotein-2; CLI; Apolipoprotein J (Apo J); TRPM-2) is the first identified extracellular mammalian chaperone and appears to be implicated in such diverse processes as sperm maturation, regulation of complement activation, programmed cell death, tissue remodelling and lipid transport. Increases in clusterin mRNA and protein have been consistently detected in apoptotic cell death paradigms, establishing clusterin gene expression as a prominent marker of apoptotic cell loss. A dual role has been shown for clusterin in that cells can be protected from damage and dead cells can be more easily removed after some types of cellular damage.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Characterization and cloning of androgen-repressed mRNAs from rat ventral prostate: J.G. Leger, et al.; BBRC 147, 196 (1987) Abstract
Apolipoprotein J: structure and tissue distribution: H.V. De Silva, et al.; Biochemistry 29, 5380 (1990) Abstract
Clusterin: the intriguing guises of a widely expressed glycoprotein: D.E. Jenne & J. Tschopp; Trends Biochem. Sci. 17, 154 (1992) Abstract
Clusterin: S.E. Jones and C. Jomary; Int. J. Biochem. Cell Biol. 34, 427 (2002), (Review) Abstract
Clusterin/Apolipoprotein J in human aging and cancer: I. Trougakos and E. Gonos; Int. J. Biochem. Cell Biol. 34, 1430 (2002) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-210-451 Revised 31-Aug-06
Polyclonal Antibody to Clusterin (human)
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SYNONYMS anti-TRPM-2 (human) PAb
anti-Apolipoprotein J (human) PAb
anti-APO-J (human) PAb
anti-CLI (human) PAb
anti-CLU (human) PAb
anti-SGP-2 (human) PAb
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY Clusterin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-451-C100   100 µg 340.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Purified IgG.
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human secretory clusterin.
SPECIFICITY: Recognizes human serum or plasma clusterin. Detects a band of ~40kDa by Western blot.
APPLICATION: ELISA (direct and indirect: 1:2’000-1:5’000)
Western Blot (1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature)
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-930 Revised 26-Feb-07
Polyclonal Antibody to Clusterin (human) (AT109)
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SYNONYMS anti-TRPM-2 (human) PAb (AT109)
anti-Apolipoprotein J (human) PAb (AT109)
anti-APO-J (human) PAb (AT109)
anti-CLI (human) PAb (AT109)
anti-CLU (human) PAb (AT109)
anti-SGP-2 (human) PAb (AT109)
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY Clusterin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-930-C050   50 µg 180.00 USD Add To Cart
Inquire
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit
CONCENTRATION: 1mg/ml
PURITY DETAIL: Epitope-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant human clusterin (aa 23-449).
SPECIFICITY: Recognizes human clusterin.
APPLICATION: Western Blot (1:1’000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
POSITIVE CONTROL: Clusterin (human) (recombinant) (Prod.No. ALX-522-089)
General Information
Clusterin (SGP-2/sulfated glycoprotein-2; CLI; Apolipoprotein J (Apo J); TRPM-2) is the first identified extracellular mammalian chaperone and appears to be implicated in such diverse processes as sperm maturation, regulation of complement activation, programmed cell death, tissue remodelling and lipid transport. Increases in clusterin mRNA and protein have been consistently detected in apoptotic cell death paradigms, establishing clusterin gene expression as a prominent marker of apoptotic cell loss. A dual role has been shown for clusterin in that cells can be protected from damage and dead cells can be more easily removed after some types of cellular damage.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Characterization and cloning of androgen-repressed mRNAs from rat ventral prostate: J.G. Leger, et al.; BBRC 147, 196 (1987) Abstract
Apolipoprotein J: structure and tissue distribution: H.V. De Silva, et al.; Biochemistry 29, 5380 (1990) Abstract
Clusterin: the intriguing guises of a widely expressed glycoprotein: D.E. Jenne & J. Tschopp; Trends Biochem. Sci. 17, 154 (1992) Abstract
Clusterin: S.E. Jones and C. Jomary; Int. J. Biochem. Cell Biol. 34, 427 (2002), (Review) Abstract
Clusterin/Apolipoprotein J in human aging and cancer: I. Trougakos and E. Gonos; Int. J. Biochem. Cell Biol. 34, 1430 (2002) Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-457 Revised 07-Feb-07
Polyclonal Antibody to Clusterin (mouse)
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SYNONYMS anti-TRPM-2 (mouse) PAb
anti-Apolipoprotein J (mouse) PAb
anti-APO-J (mouse) PAb
anti-CLI (mouse) PAb
anti-CLU (mouse) PAb
anti-SGP-2 (mouse) PAb
PRODUCT LINE Cell Cycle
PRODUCT CATEGORY Clusterin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-457-C100   100 µg 310.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Purified IgG.
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant mouse nuclear clusterin.
SPECIFICITY: Recognizes mouse serum or plasma clusterin.
APPLICATION: ELISA (direct and indirect: 1:2’000-1:5’000)
Western Blot (1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature)
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
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