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14-3-3 Proteins / Related Products
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ALX-210-708 Revised 30-Jun-06
Polyclonal Antibody to 14-3-3 (human)
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY 14-3-3 Proteins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-708-C100   100 µg 320.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
CONCENTRATION: 0.1mg/ml
PURITY DETAIL: Protein A-affinity purified IgG.
FORMULATION: Liquid. In 0.05M sodium phosphate buffer containing 0.1% sodium azide and 0.2% gelatin.
IMMUNOGEN: Synthetic peptide corresponding to aa 221-242 of 14-3-3 protein family members.
SPECIFICITY: Recognizes human 14-3-3 protein family members.
APPLICATION: Western Blot (2.5µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
HANDLING: Do not freeze.
General Information

General Literature References
[1] 14-3-3 proteins. Hot numbers in signal transduction: P.D. Burbelo and A. Hall; Curr. Biol. 5, 95 (1995) Abstract
[2] Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteins: D.H. Jones, et al.; FEBS Lett. 368, 55 (1995) Abstract
[3] 14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteins: A. Aitken, et al.; TIBS 17, 498 (1992), (Review) Abstract
[4] Evolutionary conservation of the 14-3-3 protein: G.J. Martens, et al.; BBRC 184, 1456 (1992) Abstract
[5] Expression and structural analysis of 14-3-3 proteins: D.H. Jones, et al.; D.H. Jones, et al. 245, 375 (1995) Abstract
[6] Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodies : H. Martin, et al.; J. Neurochem. 63, 2259 (1994) Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-215-021 Revised 21-Jul-06
Polyclonal Antibody to 14-3-3β
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SYNONYMS anti-KCIP-1 PAb
anti-Protein Kinase C Inhibitor Protein 1 PAb
anti-Protein 1054 PAb
anti-14-3-3α PAb
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY 14-3-3 Proteins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-215-021-R100   100 µl 290.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Sheep
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. Neat serum. Contains no preservatives.
IMMUNOGEN: Synthetic peptide corresponding to aa 1-8 (T1MDKSELV8C) of 14-3-3β.
SPECIFICITY: Recognizes human, mouse, rat, sheep and bovine 14-3-3β.
APPLICATION: ELISA
Immunohistochemistry (1:600)
Western Blot (1:3000)
Optimal condition must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein: H. Martin, et al.; FEBS Lett. 331, 296 (1993) Abstract; Full Text
Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodies: H. Martin, et al.; J. Neurochem. 63, 2259 (1994) Abstract
Purification of 14-3-3 protein and analysis of isoforms in chicken brain: Y. Patel, et al.; Biochim. Biophys. Acta 1222, 405 (1994) Abstract
Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteins: D.H. Jones, et al.; FEBS Lett. 368, 55 (1995) Abstract; Full Text
Expression and structural analysis of 14-3-3 proteins: D.H. Jones, et al.; J. Mol. Biol. 245, 375 (1995) Abstract
Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation: C.P. Wheeler-Jones, et al.; Biochem. J. 315, 41 (1996) Abstract; Full Text
14-3-3 inhibits the Dictyostelium myosin II heavy-chain-specific protein kinase C activity by a direct interaction: identification of the 14-3-3 binding domain: M. Matto-Yelin, et al.; Mol. Biol. Cell 8, 1889 (1997) Abstract; Full Text
Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease: J. Wiltfang, et al.; J. Neurochem. 73, 2485 (1999) Abstract
Functional specificity in 14-3-3 isoform interactions through dimer formation and phosphorylation. Chromosome location of mammalian isoforms and variants: A. Aitken; Plant Mol. Biol. 50, 993 (2002) Abstract
Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain: H.C. Baxter, et al.; Neuroscience 109, 5 (2002) Abstract
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1: H.K. Chen, et al.; Cell 113, 457 (2003) Abstract
Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein: P. Steinacker, et al.; Mol. Cell. Biol. 25, 1339 (2005) Abstract; Full Text
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-215-022 Revised 21-Jul-06
Polyclonal Antibody to 14-3-3ε (CT)
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SYNONYMS anti-KCIP-1 PAb (CT)
anti-Protein Kinase C Inhibitor Protein 1 PAb (CT)
anti-14-3-3E PAb (CT)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY 14-3-3 Proteins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-215-022-R100   100 µl 290.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Sheep
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. Neat serum. Contains no preservatives.
IMMUNOGEN: Synthetic peptide corresponding to aa 239-255 (CG239EEQNKEALQDVEDENQ255) of 14-3-3ε.
SPECIFICITY: Recognizes human, mouse, rat, sheep, bovine and chicken 14-3-3ε.
APPLICATION: ELISA
Immunohistochemistry
Western Blot (1:3000)
Optimal condition must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein: H. Martin, et al.; FEBS Lett. 331, 296 (1993) Abstract; Full Text
Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodies: H. Martin, et al.; J. Neurochem. 63, 2259 (1994) Abstract
Purification of 14-3-3 protein and analysis of isoforms in chicken brain: Y. Patel, et al.; Biochim. Biophys. Acta 1222, 405 (1994) Abstract
Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteins: D.H. Jones, et al.; FEBS Lett. 368, 55 (1995) Abstract; Full Text
Expression and structural analysis of 14-3-3 proteins: D.H. Jones, et al.; J. Mol. Biol. 245, 375 (1995) Abstract
Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation: C.P. Wheeler-Jones, et al.; Biochem. J. 315, 41 (1996) Abstract; Full Text
14-3-3 inhibits the Dictyostelium myosin II heavy-chain-specific protein kinase C activity by a direct interaction: identification of the 14-3-3 binding domain: M. Matto-Yelin, et al.; Mol. Biol. Cell 8, 1889 (1997) Abstract; Full Text
Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease: J. Wiltfang, et al.; J. Neurochem. 73, 2485 (1999) Abstract
Functional specificity in 14-3-3 isoform interactions through dimer formation and phosphorylation. Chromosome location of mammalian isoforms and variants: A. Aitken; Plant Mol. Biol. 50, 993 (2002) Abstract
Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain: H.C. Baxter, et al.; Neuroscience 109, 5 (2002) Abstract
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1: H.K. Chen, et al.; Cell 113, 457 (2003) Abstract
Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein: P. Steinacker, et al.; Mol. Cell. Biol. 25, 1339 (2005) Abstract; Full Text
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-215-023 Revised 21-Jul-06
Polyclonal Antibody to 14-3-3η
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SYNONYMS anti-KCIP-1 PAb
anti-Protein Kinase C Inhibitor Protein 1 PAb
anti-Protein AS1 PAb
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY 14-3-3 Proteins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-215-023-R100   100 µl 290.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Sheep
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. Neat serum. Contains no preservatives.
IMMUNOGEN: Synthetic peptide corresponding to aa 1-11 (G1DREQLLQRAR11C) of 14-3-3η.
SPECIFICITY: Recognizes human, mouse, rat, sheep, bovine and chicken 14-3-3η.
APPLICATION: Immunohistochemistry (1:3200)
Western Blot (1:3000)
Optimal condition must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein: H. Martin, et al.; FEBS Lett. 331, 296 (1993) Abstract; Full Text
Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodies: H. Martin, et al.; J. Neurochem. 63, 2259 (1994) Abstract
Purification of 14-3-3 protein and analysis of isoforms in chicken brain: Y. Patel, et al.; Biochim. Biophys. Acta 1222, 405 (1994) Abstract
Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteins: D.H. Jones, et al.; FEBS Lett. 368, 55 (1995) Abstract; Full Text
Expression and structural analysis of 14-3-3 proteins: D.H. Jones, et al.; J. Mol. Biol. 245, 375 (1995) Abstract
Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation: C.P. Wheeler-Jones, et al.; Biochem. J. 315, 41 (1996) Abstract; Full Text
14-3-3 inhibits the Dictyostelium myosin II heavy-chain-specific protein kinase C activity by a direct interaction: identification of the 14-3-3 binding domain: M. Matto-Yelin, et al.; Mol. Biol. Cell 8, 1889 (1997) Abstract; Full Text
Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease: J. Wiltfang, et al.; J. Neurochem. 73, 2485 (1999) Abstract
Functional specificity in 14-3-3 isoform interactions through dimer formation and phosphorylation. Chromosome location of mammalian isoforms and variants: A. Aitken; Plant Mol. Biol. 50, 993 (2002) Abstract
Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain: H.C. Baxter, et al.; Neuroscience 109, 5 (2002) Abstract
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1: H.K. Chen, et al.; Cell 113, 457 (2003) Abstract
Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein: P. Steinacker, et al.; Mol. Cell. Biol. 25, 1339 (2005) Abstract; Full Text
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-215-024 Revised 21-Jul-06
Polyclonal Antibody to 14-3-3γ
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SYNONYMS anti-KCIP-1 PAb
anti-Protein Kinase C Inhibitor Protein 1 PAb
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY 14-3-3 Proteins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-215-024-R100   100 µl 290.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Sheep
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. Neat serum. Contains no preservatives.
IMMUNOGEN: Synthetic peptide corresponding to aa 1-10 (V1DREQLVQKA10C) of 14-3-3γ.
SPECIFICITY: Recognizes human, mouse, rat, sheep, bovine and chicken 14-3-3γ.
APPLICATION: ELISA
Immunohistochemistry (1:800)
Western Blot (1:6’000-1:12’000)
Optimal condition must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein: H. Martin, et al.; FEBS Lett. 331, 296 (1993) Abstract; Full Text
Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodies: H. Martin, et al.; J. Neurochem. 63, 2259 (1994) Abstract
Purification of 14-3-3 protein and analysis of isoforms in chicken brain: Y. Patel, et al.; Biochim. Biophys. Acta 1222, 405 (1994) Abstract
Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteins: D.H. Jones, et al.; FEBS Lett. 368, 55 (1995) Abstract; Full Text
Expression and structural analysis of 14-3-3 proteins: D.H. Jones, et al.; J. Mol. Biol. 245, 375 (1995) Abstract
Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation: C.P. Wheeler-Jones, et al.; Biochem. J. 315, 41 (1996) Abstract; Full Text
14-3-3 inhibits the Dictyostelium myosin II heavy-chain-specific protein kinase C activity by a direct interaction: identification of the 14-3-3 binding domain: M. Matto-Yelin, et al.; Mol. Biol. Cell 8, 1889 (1997) Abstract; Full Text
Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease: J. Wiltfang, et al.; J. Neurochem. 73, 2485 (1999) Abstract
Functional specificity in 14-3-3 isoform interactions through dimer formation and phosphorylation. Chromosome location of mammalian isoforms and variants: A. Aitken; Plant Mol. Biol. 50, 993 (2002) Abstract
Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain: H.C. Baxter, et al.; Neuroscience 109, 5 (2002) Abstract
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1: H.K. Chen, et al.; Cell 113, 457 (2003) Abstract
Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein: P. Steinacker, et al.; Mol. Cell. Biol. 25, 1339 (2005) Abstract; Full Text
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-215-025 Revised 21-Jul-06
Polyclonal Antibody to 14-3-3ε (NT)
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SYNONYMS anti-KCIP-1 PAb (NT)
anti-Protein Kinase C Inhibitor Protein 1 PAb (NT)
anti-14-3-3E PAb (NT)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY 14-3-3 Proteins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-215-025-R100   100 µl 290.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Sheep
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. Neat serum. Contains no preservatives.
IMMUNOGEN: Synthetic peptide corresponding to aa 1-12 (M1DDREDLVYQAK12C) of 14-3-3ε.
SPECIFICITY: Recognizes human, mouse, rat, sheep, bovine and chicken 14-3-3ε.
APPLICATION: ELISA
Immunohistochemistry (1:400)
Western Blot (1:3000)
Optimal condition must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein: H. Martin, et al.; FEBS Lett. 331, 296 (1993) Abstract; Full Text
Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodies: H. Martin, et al.; J. Neurochem. 63, 2259 (1994) Abstract
Purification of 14-3-3 protein and analysis of isoforms in chicken brain: Y. Patel, et al.; Biochim. Biophys. Acta 1222, 405 (1994) Abstract
Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteins: D.H. Jones, et al.; FEBS Lett. 368, 55 (1995) Abstract; Full Text
Expression and structural analysis of 14-3-3 proteins: D.H. Jones, et al.; J. Mol. Biol. 245, 375 (1995) Abstract
Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation: C.P. Wheeler-Jones, et al.; Biochem. J. 315, 41 (1996) Abstract; Full Text
14-3-3 inhibits the Dictyostelium myosin II heavy-chain-specific protein kinase C activity by a direct interaction: identification of the 14-3-3 binding domain: M. Matto-Yelin, et al.; Mol. Biol. Cell 8, 1889 (1997) Abstract; Full Text
Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease: J. Wiltfang, et al.; J. Neurochem. 73, 2485 (1999) Abstract
Functional specificity in 14-3-3 isoform interactions through dimer formation and phosphorylation. Chromosome location of mammalian isoforms and variants: A. Aitken; Plant Mol. Biol. 50, 993 (2002) Abstract
Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain: H.C. Baxter, et al.; Neuroscience 109, 5 (2002) Abstract
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1: H.K. Chen, et al.; Cell 113, 457 (2003) Abstract
Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein: P. Steinacker, et al.; Mol. Cell. Biol. 25, 1339 (2005) Abstract; Full Text
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-215-026 Revised 21-Jul-06
Polyclonal Antibody to 14-3-3β/ζ (phosphorylated) (pSer185)
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SYNONYMS anti-KCIP-1 (phosphorylated) (pSer185) PAb
anti-Protein Kinase C Inhibitor Protein 1 (phosphorylated) (pSer185) PAb
anti-Protein 1054 (phosphorylated) (pSer185) PAb
anti-14-3-3α/δ (phosphorylated) (pSer185) PAb
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY 14-3-3 Proteins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-215-026-R100   100 µl 270.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Sheep
SOURCE/HOST: From sheep.
PURITY DETAIL: Affinity-purified.
FORMULATION: Liquid. Contains no preservatives.
IMMUNOGEN: Synthetic phosphorylated peptide corresponding to aa 181-190 (E181ILNpSPEKAC190) of 14-3-3β and aa 180-189 of 14-3-3ζ.
SPECIFICITY: Recognizes human, mouse, rat, sheep and bovine 14-3-3β and 14-3-3ζ.
APPLICATION: Western Blot (1:300)
Optimal condition must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Phospho-specific AntibodiesPolyclonal Antibodies
 
 
ALX-215-027 Revised 21-Jul-06
Polyclonal Antibody to 14-3-3σ
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SYNONYMS anti-KCIP-1 PAb
anti-Protein Kinase C Inhibitor Protein 1 PAb
anti-Stratifin PAb
anti-SFN PAb
anti-Epithelial Cell Marker Protein 1 PAb
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY 14-3-3 Proteins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-215-027-R100   100 µl 270.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Sheep
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. Neat serum. Contains no preservatives.
IMMUNOGEN: Synthetic peptide corresponding to aa 1-10 (M1ERASLIQKA10C) of 14-3-3σ.
SPECIFICITY: Recognizes human, mouse, rat, sheep, bovine and chicken 14-3-3σ.
APPLICATION: Western Blot (1:3000)
Optimal condition must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
A nonphosphorylated 14-3-3 binding motif on exoenzyme S that is functional in vivo: M.L. Henriksson, et al.; Eur. J. Biochem. 269, 4921 (2002) Abstract; Full Text
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-215-028 Revised 17-Aug-06
Polyclonal Antibody to 14-3-3τ
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SYNONYMS anti-14-3-3θ PAb
anti-KCIP-1 PAb
anti-Protein Kinase C Inhibitor Protein 1 PAb
anti-HS1 Protein PAb
anti-T Cell Protein PAb
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY 14-3-3 Proteins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-215-028-R100   100 µl 290.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Sheep
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. Neat serum. Contains no preservatives.
IMMUNOGEN: Synthetic peptide corresponding to aa 1-10 (M1EKTELIQKA10C) of 14-3-3τ.
SPECIFICITY: Recognizes human, mouse, rat, sheep, bovine and chicken 14-3-3τ.
APPLICATION: ELISA
Immunohistochemistry (1:60)
Western Blot (1:3000)
Optimal condition must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein: H. Martin, et al.; FEBS Lett. 331, 296 (1993) Abstract; Full Text
Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodies: H. Martin, et al.; J. Neurochem. 63, 2259 (1994) Abstract
Purification of 14-3-3 protein and analysis of isoforms in chicken brain: Y. Patel, et al.; Biochim. Biophys. Acta 1222, 405 (1994) Abstract
Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteins: D.H. Jones, et al.; FEBS Lett. 368, 55 (1995) Abstract; Full Text
Expression and structural analysis of 14-3-3 proteins: D.H. Jones, et al.; J. Mol. Biol. 245, 375 (1995) Abstract
Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation: C.P. Wheeler-Jones, et al.; Biochem. J. 315, 41 (1996) Abstract; Full Text
14-3-3 inhibits the Dictyostelium myosin II heavy-chain-specific protein kinase C activity by a direct interaction: identification of the 14-3-3 binding domain: M. Matto-Yelin, et al.; Mol. Biol. Cell 8, 1889 (1997) Abstract; Full Text
Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease: J. Wiltfang, et al.; J. Neurochem. 73, 2485 (1999) Abstract
Functional specificity in 14-3-3 isoform interactions through dimer formation and phosphorylation. Chromosome location of mammalian isoforms and variants: A. Aitken; Plant Mol. Biol. 50, 993 (2002) Abstract
Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain: H.C. Baxter, et al.; Neuroscience 109, 5 (2002) Abstract
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1: H.K. Chen, et al.; Cell 113, 457 (2003) Abstract
Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein: P. Steinacker, et al.; Mol. Cell. Biol. 25, 1339 (2005) Abstract; Full Text
Further Categories Containing This Product: