ALEXIS Biochemicals: Caspase-2 (active) (human) (recombinant) (high purity)

ALX-522-083

Revised 24-Mar-05

Caspase-2 (active) (human) (recombinant) (high purity)
SYNONYMS	ICH-1 (active) (human) (recombinant) (high purity) CASP-2 (active) (human) (recombinant) (high purity) ICH-1 protease (active) (human) (recombinant) (high purity) ICH-1L/1S (active) (human) (recombinant) (high purity)
PRODUCT LINE	Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY	Caspases

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-522-083-C005		5 µg	180.00 USD

Product Specification

MW:	~31kDa; α-subunit: ~19kDa; β-subunit: ~12kDa.
EC:	3.4.22.-
SOURCE/HOST:	Produced in E. coli.
CONCENTRATION:	0.072mg/ml.
PURITY:	≥95% (SDS-PAGE)
FORMULATION:	Liquid. 5µg of recombinant protein in 20mM HEPES, pH 7.5, containing 4mM DTT, 10% sucrose (w/v) and 150mM NaCl.
SPECIFIC ACTIVITY:	~80'000U/mg. One unit is defined as the amount of enzyme that cleaves 1nmol of the caspase substrate Ac-VDVAD-pNA (Prod. No. ALX-260-059) per hour at 37°C in a reaction solution containing 100mM MES, pH 6.5, 10% PEG 600, 10mM DTT and 0.1% CHAPS.
SHIPPING:	SHIPPED ON DRY ICE
LONG TERM STORAGE:	-80°C
HANDLING:	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.

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Product Specific Literature References

Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway: A. Schweizer, et al.; J. Biol. Chem. 278, 42441 (2003) Abstract; Full Text

General Information

MANUFACTURER

Manufactured by Apotech Corporation.

Further Categories Containing This Product:

Enzymes • Recombinant Proteins / Fusion Proteins

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