ALEXIS Biochemicals: Chaetomellic acid A . disodium salt

ALX-270-064

Revised 14-Jul-03

Chaetomellic acid A . disodium salt
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Farnesylation / Isoprenylation Reagents

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-064-M001		1 mg	30.00 USD
ALX-270-064-M005		5 mg	70.00 USD
ALX-270-064-M010		10 mg	130.00 USD

Product Specification

FORMULA:	C₁₉H₃₂O₄. 2Na
MW:	324.5 . 46.0
PURITY:	≥98%
APPEARANCE:	White solid.
SOLUBILITY:	Soluble in warm water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Potent inhibitor of farnesyltransferase in isolated enzyme assays but is inactive in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and II.

Product Specific Literature References

Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo: J.B. Gibbs, et al.; J. Biol. Chem. 268, 7617 (1993) Abstract; Full Text
Inhibitors of Ras farnesyltransferases: F. Tamanoi; TIBS 18, 349 (1993), (Review) Abstract

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