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TNF-alpha & TNF Receptors / Related Products
You are here: Product Lines > Chemokines & Cytokines > Adipokines / Related Products > TNF-alpha & TNF Receptors / Related Products
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ALX-522-014 Revised 03-May-07
TNF-R2 (human):Fc (human) (recombinant)
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SYNONYMS TNF-R 80kDa (human):Fc (human) (recombinant)
CD120b (human):Fc (human) (recombinant)
p75 (human):Fc (human) (recombinant)
TNFRSF 1B (human):Fc (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY TNF-R2
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-522-014-C050   50 µg 360.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
MW: ~75kDa (reducing SDS-PAGE).
SOURCE/HOST: Produced in HEK 293 cells. The extracellular domain of human TNF-R2 (aa 1-257) is fused to the Fc portion of human IgG1.
CONCENTRATION: 1mg/ml after reconstitution.
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Lyophilized. Contains PBS.
ENDOTOXIN CONTENT: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION: Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
SPECIFICITY: Binds human and mouse TNF-α (tumor necrosis factor-α).
APPLICATION: Detection of membrane-bound TNF-α in combination with PAb to human IgG1 (Prod. No. ALX-211-500 (FITC), ALX-211-501 (R-PE), ALX-211-502 (Biotin)).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -20°C.
HANDLING: After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Specific Literature References
Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors: N. Holler, et al.; J. Immunol. Methods 237, 159 (2000) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link P20333: TNF-R2 (human) (precursor)
AfCs Signalling Gateway link A002346: TNF-R2 (mouse)
MANUFACTURER Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
 
 
ALX-850-048 Revised 17-Apr-08
TNF-R2, Soluble (human) ELISA Kit
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SYNONYMS p75, Soluble (human) ELISA Kit
CD120b, Soluble (human) ELISA Kit
TNF-R 80kDa, Soluble (human) ELISA Kit
TNFRSF 1B, Soluble (human) ELISA Kit
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY TNF-R2
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-850-048-KI01   1 Kit 619.00 USD Add To Cart
Product Specification
SENSITIVITY: 0.09ng/ml (range 0.16 to 10ng/ml)
QUANTITY: 96 wells (~80 tests).
APPLICATION: For the quantitative determination of soluble human TNF-R2 in cell culture supernatants,  serum and other body fluids.
SHIPPING: SHIPPED ON BLUE ICE
HANDLING: Store controls at -20°C. Store rest of the kit at +4°C.
Product Specific Literature References
Serum levels of tumor necrosis factor (TNF), soluble receptors for TNF (55- and 75-kDa sTNFr), and soluble CD14 (sCD14) in epithelial ovarian cancer: A. Gadducci, et al.; Gynecol. Oncol. 58, 184 (1995) Abstract
High blood soluble receptor p80 for tumour necrosis factor-alpha is associated with erythropoietin resistance in haemodialysis patients: A. Kato, et al.; Nephrol. Dial. Transplant. 16, 1838 (2001) Abstract; Full Text
General Information
MANUFACTURER Manufactured by Bender MedSystems.
Further Categories Containing This Product:
CD Kits & SetsELISA & EIA Kits
 
 
ALX-522-049 Revised 18-Jul-06
XEDAR (human):Fc (human) (recombinant)
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SYNONYMS X-linked Ectodysplasin-A2 Receptor (human):Fc (human) (recombinant)
EDA-A2 Receptor (human):Fc (human) (recombinant)
EDA2R (human):Fc (human) (recombinant)
TNFRSF27 (human):Fc (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY EDA & EDAR, Troy / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-522-049-C050   50 µg 360.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
MW: ~47kDa (SDS-PAGE).
SOURCE/HOST: Produced in HEK 293 cells. The cysteine-rich domain of human XEDAR (X-linked ectodysplasin-A2 receptor) (aa 1-133) is fused to the Fc portion of human IgG1.
CONCENTRATION: 1mg/ml after reconstitution
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Lyophilized. Contains PBS.
ENDOTOXIN CONTENT: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION: Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
SPECIFICITY: Binds human EDA-A2 (ectodysplasin-A2).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -20°C.
Product Specific Literature References
Mutations leading to X-linked hypohidrotic ectodermal dysplasia affect three major functional domains in the tumor necrosis factor family member ectodysplasin-A: P. Schneider, et al.; J. Biol. Chem. 276, 18819 (2001) Abstract; Full Text
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q9HAV5: XEDAR (human)
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors: M. Yan, et al.; Science 290, 523 (2000) Abstract
 
 

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