ALEXIS Biochemicals: PQ401

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ALX-270-459

Revised 22-May-07

PQ401
SYNONYMS	IGF-IR Inhibitor N-(5-Chloro-2-methoxyphenyl)-N’-(2-methyl-4-quinolinyl)urea
PRODUCT LINE	Chemokines & Cytokines
PRODUCT CATEGORY	Insulin-like Growth Factors [IGFs] & Receptors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-459-M001		1 mg	40.00 USD
ALX-270-459-M005		5 mg	160.00 USD

Product Specification

FORMULA:	C₁₈H₁₆ClN₃O₂
MW:	341.8
CAS NUMBER:	196868-63-0
PURITY:	≥98% (HPLC)
APPEARANCE:	Off-white solid.
SOLUBILITY:	Soluble in DMSO (10mg/ml) or methanol (7mg/ml).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
MELTINGPOINT:	208-210°C

Product Description

Potent inhibitor of insulin-like growth factor I receptor (IGF-IR) signalling and breast cancer cell growth in culture and in vivo.

Product Specific Literature References

Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth: K.L. Gable, et al.; Mol. Cancer Ther. 5, 1079 (2006) Abstract

Further Categories Containing This Product:

Antitumor Agents (Anti-proliferative) • Tyrosine Kinase Inhibitors

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