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TNF & TNF Receptor Superfamily / Related Products
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ALX-201-073 Revised 20-Nov-08
KillerTRAIL™, Soluble (human) (recombinant)
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SYNONYMS Apo-2L, Soluble (human) (recombinant)
TNFSF 10, Soluble (human) (recombinant)
CD253, Soluble (human) (recombinant)
PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY TRAIL [Apo-2L]
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-073-C020   20 µg 360.00 USD Add To Cart
ALX-201-073-3020 SuperPack 3x20 µg 720.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST: Produced in E. coli. The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a His-tag and a linker peptide.
CONCENTRATION: 0.5mg/ml   
PURITY: ≥99% (SDS-PAGE)
PURITY DETAIL: Affinity purified. Sterile filtered.
FORMULATION: Liquid. In 20mM HEPES, pH 7.9, 120mM sodium chloride, 0.01% Tween 20, 1% sucrose and 1mM DTT.
ENDOTOXIN CONTENT: ≤0.004EU/μg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION: For a special storage and dilution buffer see KillerTRAIL™ Storage and Dilution Buffer (Prod. No. ALX-505-005).
SPECIFICITY: Binds to human and mouse TRAIL receptors and osteoprotegerin (OPG).
BIOLOGICAL ACTIVITY: Induces apoptosis in a concentration range of 10-100ng/ml.
Note: Does not require a cross-linking enhancer for its potent biological activity. For cell lines that require extensive cross-linking of the TRAIL-Rs for killing (e.g. Jurkat) use SuperKillerTRAIL™ (Prod. No. ALX-201-115).
SPECIFIC ACTIVITY: ED50: 20ng/ml (BJAB cells)
SHIPPING: SHIPPED ON DRY ICE
LONG TERM STORAGE: -80°C
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.
Product Images
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Product Specific Literature References
The cytokines tumor necrosis factor-α (TNF-α) and TNF-related apoptosis-inducing ligand differentially modulate proliferation and apoptotic pathways in human keratinocytes expressing the human papilloma: J.R. Basile, et al.; J. Biol. Chem. 276, 22522 (2001) Abstract; Full Text
The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines: Q. Liao, et al.; FEBS Lett. 503, 151 (2001) Abstract
TRAIL (Apo2L) suppresses growth of primary human leukemia and myelodysplasia progenitors: M. Plasilova, et al.; Leukemia 16, 67 (2002) Abstract; Full Text
TRAIL and its receptors in the colonic epithelium: a putative role in the defense of viral infections: J. Sträter, et. al.; Gastroenterology 122, 659 (2002) Abstract
Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1: M. MacFarlane, et al.; Cell Death Differ. 12, 773 (2005) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link P50591: TRAIL (human)
AfCS Signalling Gateway link A002862: TRAIL (mouse)
Related Products
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
 
 
APO-54N-029 Revised 05-Dec-08
LIGHT, Soluble (human) Detection Set [For ELISA Application]
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SYNONYMS HVEML, Soluble (human) Detection Set [For ELISA Application]
TNFSF 14, Soluble (human) Detection Set [For ELISA Application]
CD258, Soluble (human) Detection Set [For ELISA Application]
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY HVEM & LIGHT / LT-betaR / DcR3 / Related Products
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APO-54N-029-KI01   1 Set 540.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY: 0.2ng/ml (range 0 to 20ng/ml).
QUANTITY: 5x96 wells
KIT/SET CONTAINS: 1 vial Standard (lyophilized) (STD).
1 vial Coating Antibody (COAT).
1 vial Detection Antibody (DET).
APPLICATION: For the quantitative determination of human LIGHT (HVEML; TNFSF 14) from biological fluids (serum, plasma and cell culture supernatant).
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
HANDLING: Avoid freeze/thaw cycles. For long term storage keep the standard (STD) at -20°C.
General Information
LIGHT (derived from "homologous to Lymphotoxins, exhibits Inducible expression, and competes with Herpes simplex virus (HSV) Glycoprotein D for Herpes virus entry mediator (HVEM /TR2), a receptor expressed by T lymphocytes")is a 29 kDa type 2 transmembrane protein that belongs to the TNF superfamily [1, 2]. It is expressed in granulocytes, monocytes, platelets, immature dendritic cells and activated T cells. LIGHT is active either as membrane-anchored or secreted (soluble) forms. Three receptors of the TNF superfamily: lymphotoxin receptor (LTR), herpesvirus entry mediator (HVEM), and decoy receptor 3 (DcR3) binds to the ligand. LIGHT is involved in T-cell regulation and dendritic cell maturation [3]. It triggers several signaling pathways such as NF-κB, non-canonical NF-κB, Stat3, ERK5 / BMK1 and JNK [4]. LIGHT is released from platelets and induces a proinflammatory state in vascular endothelial cells [5]. It suppress tumor formation in vivo by inducing apoptotic cell death. Embryonic stem (ES) cells are differentiated in the presence of LIGHT [6]. Mice overexpressing LIGHT spontaneously develop severe autoimmune disease. LIGHT has been reported to increase in Rhumatoid Arthritis (RA) patients and to induce a RANKL ­dependent and -independent osteoclasts formation [7].
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link O43557: Tumor Necrosis Factor Ligand Superfamily Member 14 (human)
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
[1] LIGHT-HVEM signaling and the regulation of T cell-mediated immunity: S.W. Granger & S. Rickert; Cytokine Growth Factor Rev. 14, 289 (2003) Abstract
[2] LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator: D.N. Mauri, et al. ; Immunity 8, 21 (1998) Abstract
[3] LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response: K. Tamada, et al. ; J. Immunol. 164, 4105 (2000) Abstract
[4] LIGHT, a member of the TNF superfamily, activates Stat3 mediated by NIK pathway: N. Nadiminty, et al. ; BBRC 359, 379 (2007) Abstract
[5] Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes: K. Otterdal, et al. ; Blood 108, 928 (2006) Abstract
[6] LIGHT induces differentiation of mouse embryonic stem cells associated with activation of ERK5: G.M. Zou, et al. ; Oncogene 25, 463 (2006) Abstract
[7] LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis: J.R. Edwards, et al. ; Arthritis Rheum. 54, 1451 (2006) Abstract
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-522-018 Revised 23-Nov-07
LIGHT, Soluble (human) (recombinant)
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SYNONYMS HVEML, Soluble (human) (recombinant)
TNFSF 14, Soluble (human) (recombinant)
CD258, Soluble (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY HVEM & LIGHT / LT-betaR / DcR3 / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-522-018-C010   10 µg 360.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
MW: ~25kDa (SDS-PAGE)
SOURCE/HOST: Produced in HEK 293 cells. The extracellular domain of human LIGHT (aa 89-240) is fused at the N-terminus to a linker peptide (10 aa) and a FLAG®-tag.
CONCENTRATION: 0.1mg/ml after reconstitution.
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Lyophilized. Contains PBS.
ENDOTOXIN CONTENT: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION: Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
SPECIFICITY: Binds to human and mouse LTβR and human HVEM and DcR3.
BIOLOGICAL ACTIVITY: Increases LNCaP (prostate cancer cell) growth.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
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Product Specific Literature References
T cell costimulation by the TNF ligand BAFF: B. Huard, et al.; J. Immunol. 167, 6225 (2001) Abstract
Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis: J. Kuai, et al.; J. Biol. Chem. 278, 14363 (2003) Abstract; Full Text
A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator: L.C. Gonzalez, et al.; PNAS 102, 1116 (2005) Abstract; Full Text
LIGHT, a member of the TNF superfamily, activates Stat3 mediated by NIK pathway: N. Nadiminty, et al.; BBRC 359, 379 (2007) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link O43557: LIGHT (human)
AfCS Signalling Gateway link A001406: LIGHT (mouse)

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
 
 
ALX-522-034 Revised 27-Mar-06
LTα3, Soluble (human) (recombinant)
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SYNONYMS TNF-β, Soluble (human) (recombinant)
TNFSF 1, Soluble (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY TNF-alpha & TNF Receptors Other Products
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ALX-522-034-C010   10 µg 200.00 USD Add To Cart
ALX-522-034-3010 SuperPack 3x10 µg 410.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
MW: ~25kDa (SDS-PAGE).
SOURCE/HOST: Produced in E. coli. The extracellular domain of human LTα3 (aa 43-205) is fused at the N-terminus to a linker peptide (10 aa) and a FLAG®-tag.
CONCENTRATION: 0.1mg/ml after reconstitution.
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Lyophilized. Contains PBS.
ENDOTOXIN CONTENT: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION: Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
SPECIFICITY: Binds to human HVEM and human and mouse TNF-R1 and TNF-R2.
BIOLOGICAL ACTIVITY: Kills human TNF-R1 positive cells.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles.
General Information
Lymphotoxin-α (LTα, TNF-β) is a 25 kDa type II soluble protein belonging to the TNF family. It is expressed as a trimer (LTα3), or with lymphotoxin-β (LTα1β2 or LTα2β1). LTα3 interacts with 3 different members of the TNF-receptor superfamily: HVEM (Prod. No. ALX-522-017), TNF-R1 (Prod. No. ALX-522-013) and TNF-R2 (Prod. No. ALX-522-014). LTα3 is expressed by activated T and B lymphocytes and is a pro-apoptotic cytokine, a pluripotent mediator of inflammtory and immune defense mechanisms, and moreover it plays an important role in regulating the generation of the peripheral lymphoid system.
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link P01374: TNF-β (human) (precursor)
AfCS Signalling Gateway link A001438: TNF-β (mouse)

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by Apotech Corporation.
Further Categories Containing This Product:
HVEM & LIGHT / LT-betaR / DcR3 / Related Products • Recombinant Proteins / Fusion Proteins
 
 
ALX-522-041 Revised 20-Jul-06
LTβR (human):Fc (human) (recombinant)
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SYNONYMS Tumor Necrosis Factor Receptor 2-related Protein
TNFRSF 3 (human):Fc (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY HVEM & LIGHT / LT-betaR / DcR3 / Related Products
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ALX-522-041-C050   50 µg 360.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
MW: Migrates as a doublet at ~56kDa and ~60kDa (SDS-PAGE).
SOURCE/HOST: Produced in HEK 293 cells. The cysteine-rich region of human LTβR (aa 1-220) is fused to the Fc portion of human IgG1.
CONCENTRATION: 1mg/ml after reconstitution.
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Lyophilized. Contains PBS.
ENDOTOXIN CONTENT: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION: Reconstitute in 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
SPECIFICITY: Binds human and mouse LIGHT and LTα1β2.
BIOLOGICAL ACTIVITY: Inhibits human LIGHT- and LTα1β2-mediated effects such as cytotoxic effects on HT29 target cells.
APPLICATION: Detection of human membrane-bound LIGHT in combination with PAb to human IgG1.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -20°C.
HANDLING: After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Specific Literature References
The lymphotoxin-β receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells: I.A. Rooney, et al.; J. Biol. Chem. 275, 14307 (2000) Abstract; Full Text
Lymphotoxin-mediated regulation of gammadelta cell differentiation by alphabeta T cell progenitors: B. Silva-Santos, et al.; Science 307, 925 (2005) Abstract
Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human: C. Bossen, et al.; J. Biol. Chem. 281, 13964 (2006) Abstract; Full Text
General Information
LTβR is a 75kDa type I transmembrane protein belonging to the TNF receptor family. It is 414 aa long and contains 4 cysteine-rich repeats in its extracellular domain. It is expressed on monocytes, fibroblasts, stromal and muscle cells. It is known to activate nuclear factor NF-κB, to interact with NIK and to induce cell death via TNF receptor-associated factor 3 (TRAF3). LTβR has two known ligands: LIGHT and LTα1β2. It has been shown to be involved in splenic architecture development, lymph node genesis and affinity maturation, as well as in the development of diabetes and colitis. It has been implicated in the induction of HIV replication and impairs prion replication in mice lacking follicular dendritic cells.
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link P36941: LTβR (human) (precursor)
AfCS Signalling Gateway link A001440: LTβR (mouse)
MANUFACTURER Manufactured by Apotech Corporation.
Related Products
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
 
 
ALX-522-092 Revised 27-Mar-06
MegaAPRIL™, Soluble (mouse) (H98) (recombinant)
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SYNONYMS rmsMegaAPRIL™ (H98)
APRIL, Soluble (mouse) (recombinant):ACRP30headless (mouse) (H98)
A-Proliferation-inducing Ligand (mouse) (recombinant):ACRP30headless (mouse) (H98)
TNFSF 13, Soluble (mouse) (recombinant):ACRP30headless (mouse) (H98)
CD256, Soluble (mouse) (recombinant):ACRP30headless (mouse) (H98)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY APRIL
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-522-092-3010   3x10 µg 440.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST: Produced in HEK 293 cells. The extracellular domain of mouse APRIL (aa 98-232) is fused at the N-terminus to a mouse ACPR30headless (aa 18-110) and a FLAG®-tag.
CONCENTRATION: 0.1mg/ml after reconstitution.
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Lyophilized. Contains PBS.
ENDOTOXIN CONTENT: ≤0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION: Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
SPECIFICITY: Binds to human and mouse BCMA and TACI. Does not bind to proteoglycans.
BIOLOGICAL ACTIVITY: Stimulates B cell proliferation.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -20°C.
HANDLING: After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
General Information
BACKGROUND/TECHNICAL INFORMATION FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth: M. Hahne, et al.; J. Exp. Med. 188, 1185 (1998) Abstract
Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI: S.A. Marsters, et al.; Curr. Biol. 10, 785 (2000) Abstract
A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth: P. Rennert, et al.; J. Exp. Med. 192, 1677 (2000) Abstract
Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS: Y. Wu, et al.; J. Biol. Chem. 275, 35478 (2000) Abstract; Full Text
APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity: G. Yu, et al.; Nat. Immunol. 1, 252 (2000) Abstract
Identification of proteoglycans as the APRIL-specific binding partners: K. Ingold, et al.; J. Exp. Med. 201, 1375 (2005) Abstract
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
 
 
ALX-801-090 Revised 28-Oct-08
Monoclonal Antibody to α-Gal Epitope (Galα1-3Galβ1-4GlcNAc-R) (M86)
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PRODUCT LINE Immunology
PRODUCT CATEGORY Xenotransplantation
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ALX-801-090-L002   3 ml 320.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
Pig
Others
CLONE: M86
ISOTYPE: Mouse IgM
FORMULATION: Liquid. Supernatant antibody.
IMMUNOGEN: Rabbit red blood cell membrane.
SPECIFICITY: Recognizes synthetic and naturally produced mouse, rat and pig Galα1-3Gal epitopes on glycoproteins and glycolipids. Does not cross-react with β-Gal glycoproteins or BSA.
APPLICATION: ELISA
Flow Cytometry
Immunohistochemistry (paraffin sections)
Western Blot
Functional Application (can be used for cytotoxicity assays for α-Gal specific pathways)
Note: Do not use non-fat milk for blocking! Many blocking agents from non-human mammal sources will cross-react with the antibody.
An antibody dilution of 1:5  is recommended. Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY:

Stable for at least 3 years when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Description
Widely described antibody against α-galactose residues with broad cross-reactivity among different species. Useful for measuring the α-Gal epitope expression on cells, glycolipids and glycoproteins, characterization of hyperacute rejection (HAR) in organ and tissue transplantations and monitoring xenotransplantation experiments. The IgM isotype mimicks in vivo reactions and can be used for cytotoxicity assays for α-Gal specific pathways (addition or presence of complement necessary). Ideal as a high-throughput screening tool for inhibitors of antibody induced cytotoxicity.
Organ transplantation from pig to human result in HAR. Humans naturally produce large quantities of anti-α-Gal antibodies, which represent 1-3% of all circulating immunoglobulins and are produced by about 1% of all B cells. When pig organs or tissues are transplanted into the human body, the IgM isotype of anti-Gal binds to α-Gal epitopes, which causes activation of the complement cascade, resulting in cell lysis. This rapid activation of complement by anti-Gal IgM is an immunological barrier that poses the greatest risk of initiating HAR. The monoclonal antibody M86 to Galα1-3Gal epitopes developed by U. Galili, et al. is an essential tool in the study of human xenotransplantation and related research.
Product Specific Literature References
A sensitive assay for measuring alpha-Gal epitope expression on cells by a monoclonal anti-Gal antibody: U. Galili, et al.; Transplantation 65, 1129 (1998) Abstract
Regulation of natural killer cell-mediated swine endothelial cell lysis through genetic remodeling of a glycoantigen: S. Miyagawa, et al.; J. Biochem. 126, 1067 (1999) Abstract
alpha-Gal Oligosaccharides: Chemistry and Potential Biomedical Application: A. Janczuk, et al.; Current Med. Chem. 6, 155 (1999) Abstract
Mechanism of delayed rejection in transgenic pig-to-primate cardiac xenotransplantation: R.H. Chen, et al.; J. Surg. Res. 90, 119 (2000) Abstract
Xenotransplantation: in vitro analysis of synthetic alpha-galactosyl inhibitors of human anti-Galalpha1-->3Gal IgM and IgG antibodies: R. Rieben, et al.; Glycobiology 10, 141 (2000) Abstract
Differential immune responses to alpha-gal epitopes on xenografts and allografts: implications for accommodation in xenotransplantation: M. Tanemura, et al.; J. Clin. Invest. 105, 301 (2000) Abstract
Differential expression of alpha-Gal epitopes on pig and mouse organs: M. Tanemura & U. Galili; Transplant. Proc. 32, 843 (2000) Abstract
The alpha-gal epitope (Gal alpha 1-3Gal beta 1-4GlcNAc-R) in xenotransplantation: U. Galili; Biochemie 83, 557 (2001) Abstract
Remodeling of the Major Pig Xenoantigen by N-Actetylglucosaminyltransferase III in Transgenic Pig: S. Miyagawa, et al.; J. Biol. Chem. 276, 39310 (2001) Abstract; Full Text
Synthesis of α-gal epitopes (Galα1-3Galβ1-4GlcNAc-R) on human tumor cells by recombinant α1,3galactosyltransferase produced in Pichia pastoris: Z.C. Chen, et al.; Glycobiology 11, 577 (2001) Abstract; Full Text
Differential expression of Galalpha1,3Gal epitopes on fetal and adult porcine hematopoietic cells: S. Gojo, et al.; Xenotransplantation 9, 297 (2002) Abstract; Full Text
Expression of alpha-gal epitopes on HeLa cells transduced wtih adenovirus containing alpha-1,3galactosyltransferase cDNA: L. Deriy, et al.; Glycobiology 12, 135 (2002) Abstract
Lack of Galactose-alpha-1,3-Galactose Expression on Porcine Endothelial Cells Prevents Complement-Induced Lysis but Not Direct Xenogeneic NK Cytotoxicity: B.C. Baumann, et al.; J. Immunol. 172, 6460 (2004) Abstract
Further Categories Containing This Product:
CD40 & CD40L [CD154] / Related Products • Monoclonal Antibodies
 
 
ALX-804-148 Revised 31-Oct-06
Monoclonal Antibody to APRIL (human) (Aprily-1)
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SYNONYMS anti-A-Proliferation-inducing Ligand (human) MAb (Aprily-1)
anti-TNFSF 13 (human) MAb (Aprily-1)
anti-CD256 (human) MAb (Aprily-1)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY APRIL
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ALX-804-148-C100   100 µg 320.00 USD Add To Cart
Product Specification