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ALX-805-026
Revised 08-Feb-05
Monoclonal Antibody to CD42c (human) (Gi27)
SYNONYMS
anti-GP1bβ (human) MAb (Gi27)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-805-026-C100
100 µg
230.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
Gi27
ISOTYPE:
Mouse IgG2b
PURITY:
>95%.
FORMULATION:
Liquid. 100µg of purified antibody in 200µl PBS containing 0.05% sodium azide.
IMMUNOGEN:
Human platelets.
SPECIFICITY:
Recognizes the human GPIbβ subunit (CD42c) of the human GPIb/IX/V (CD42a/CD42b/CD42c/CD42d) complex.
APPLICATION:
Immunoprecipitation
Western Blot (1:20)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
Product Specific Literature References
S.F. Schlossman, et al.; Oxford University Press - Leucocyte Typing V 1309 (1995)
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-805-027
Revised 20-Jan-06
Monoclonal Antibody to CD9 (human) (Gi15)
SYNONYMS
anti-p24 (human) MAb (Gi15)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-805-027-C100
100 µg
230.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
Gi15
ISOTYPE:
Mouse IgG2b
PURITY:
>95%.
FORMULATION:
Liquid. 100µg of purified antibody in 200µl PBS containing 0.05% sodium azide.
IMMUNOGEN:
Human platelets.
SPECIFICITY:
Recognizes human CD9 (p29).
APPLICATION:
Immunoprecipitation
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-805-029
Revised 12-Jan-05
Monoclonal Antibody to CD31 (human) (Gi34)
SYNONYMS
anti-PECAM-1 (human) Mab (Gi34)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-805-029-C100
100 µg
230.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
Gi34
ISOTYPE:
Mouse IgG1
PURITY:
>95%.
FORMULATION:
Liquid. 100µg of purified antibody in 200µl PBS containing 0.05% sodium azide.
IMMUNOGEN:
Human platelets.
SPECIFICITY:
Recognizes the Ig loops 2-3 of human CD31.
APPLICATION:
Antigen Capture Assay
Immunoprecipitation
Western Blot (1:20)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
Product Specific Literature References
S.F. Schlossman, et al.,; Oxford University Press - Leucocyte Typing V 1261 (1995)
Further Categories Containing This Product:
Immunoglobulin Superfamily Cell Adhesion Molecules [IgSF CAMs] / Related Products
•
Monoclonal Antibodies
ALX-805-030
Revised 08-Feb-05
Monoclonal Antibody to CD49b/CD29 Complex (human) (Gi14)
SYNONYMS
anti-GPla/lla Complex (human) MAb (Gi14)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-805-030-C100
100 µg
230.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
Gi14
ISOTYPE:
Mouse IgG1
CONCENTRATION:
0.5mg/ml
PURITY:
>95%.
FORMULATION:
Liquid. Purified antibody in PBS containing 0.05% sodium azide.
IMMUNOGEN:
Human platelets.
SPECIFICITY:
Recognizes the GPIa subunit (CD49b) of the human GPIa/IIa (CD49b/CD29) complex.
APPLICATION:
Flow Cytometry
Immunohistochemistry (frozen sections, paraffin sections)
Immunoprecipitation
Antigen Capture Assay
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
Further Categories Containing This Product:
Monoclonal Antibodies
•
Integrins / Related Products
ALX-805-037
Revised 13-Feb-07
Monoclonal Antibody to CD40L (human) (blocking) (MK13A4)
SYNONYMS
anti-CD154 (human) MAb (blocking) (MK13A4)
anti-gp39 (human) MAb (blocking) (MK13A4)
anti-TNFSF 5 (human) MAb (blocking) (MK13A4)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CD40 & CD40L [CD154] / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-805-037-C100
Purified
100 µg
259.00 USD
ALX-805-037B-T100
Biotin
100 tests
308.00 USD
ALX-805-037F-T100
FITC
100 tests
308.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
MK13A4
ISOTYPE:
Mouse IgG1
QUANTITY:
MK13A4
: 100µl
MK13A4-Biotin
: 1ml
MK13A4-FITC
: 1ml
FORMULATION:
MK13A4
: Liquid. 1mg/ml in PBS.
MK13A4-Biotin and -FITC
: Liquid. In 50mM TRIS, pH 7.4, containing 100mM sodium chloride, 1% BSA and 0.02% sodium azide.
IMMUNOGEN:
Recombinant human CD40L (CD154).
SPECIFICITY:
Recognizes human CD40L.
APPLICATION:
Flow Cytometry
Functional Application
(blocks binding of CD40L to its receptor CD40)
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-805-038
Revised 23-Jul-08
Monoclonal Antibody to Fas (human) (2R2)
SYNONYMS
anti-CD95 (human) MAb (2R2)
anti-APO-1 (human) MAb (2R2)
anti-TNFRSF 6 MAb (human) (2R2)
PRODUCT LINE
Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY
Fas Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-805-038-C100
100 µg
340.00 USD
ALX-805-038B-C100
Biotin
100 µg
390.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
2R2
ISOTYPE:
Mouse IgG3
SOURCE/HOST:
Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE).
PURITY DETAIL:
Protein A-affinity purified.
FORMULATION:
2R2
: Liquid. In PBS containing 1% BSA. Contains no preservatives.
2R2-Biotin
: Liquid. In PBS.
IMMUNOGEN:
Mouse L cells stably overexpressing human Fas (CD95; APO-1).
SPECIFICITY:
Recognizes human Fas.
APPLICATION:
2R2:
Flow Cytometry
Functional Application (induces apoptosis - no cross-linking required).
- Can be used in DISC (death-inducing signalling complex assays): Co-immunoprecipitates FADD and caspase-8 after receptor activation.
2R2-Biotin:
Flow Cytometry
Immunocytochemistry
Immunohistochemistry (frozen sections, paraffin sections)
- Recommended working dilutions are 1:200-1:1000.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
HANDLING:
For long term storage keep unconjugated antibody at -20°C. Avoid freeze/thaw cycles. Keep conjugated formats at +4°C. Do not freeze. Protect from light.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis:
D. Ferrari, et al.; J. Exp. Med.
188
, 979 (1998)
Abstract
;
Full Text
Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction:
S. Wesselborg, et al.; Blood
93
, 3053 (1999)
Abstract
;
Full Text
IL-10 induces apoptosis in human monocytes involving the CD95 receptor/ligand pathway:
M. Schmidt, et al.; Eur. J. Immunol.
30
, 1769 (2000)
Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION
IHC (PS) Antigen Retrieval: we recommend using a citric acid solution together with microwave retrieval (5 x 5 minutes at high intensity).
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-805-039
Revised 19-May-05
Monoclonal Antibody to CD36 (63)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-805-039-C100
100 µg
390.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
CLONE:
63
ISOTYPE:
Mouse IgA
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. Protein L purified antibody in PBS containing 20% glycerol.
IMMUNOGEN:
Recombinant mouse CD36.
SPECIFICITY:
Recognizes mouse and rat CD36.
APPLICATION:
Flow Cytometry (1:1’000)
Immunocytochemistry (1:1’000)
Immunoprecipitation (1:1’000)
Functional Application (blocks uptake of oxidized LDL by mouse macrophages and prevents foam cell formation
in vitro
).
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
Further Categories Containing This Product:
Obesity & Diabetes Other Products
•
Monoclonal Antibodies
ALX-805-040
Revised 04-Jan-06
Monoclonal Antibody to CD43 (human) (MEM-59)
SYNONYMS
anti-Leukosialin (human) MAb (MEM-59)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-805-040-C100
100 µg
210.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
MEM-59
ISOTYPE:
Mouse IgG1
FORMULATION:
Contains 0.05% sodium azide.
IMMUNOGEN:
Human T lymphocytes.
SPECIFICITY:
Recognizes human CD43 (leukosialin).
APPLICATION:
Flow Cytometry
Immunohistochemistry
Immunoprecipitation
Western Blot
Functional Application (induces apoptosis in hemopoietic progenitor cells)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
Product Specific Literature References
Characterization of a 95 kDa human leucocyte sialoglycoprotein: its identity with CD43, gpL115, leukosialin and sialophorin:
I. Stefanova, et al.; Folia Biol (Praha)
34
, 255 (1988)
Abstract
MEM-59 monoclonal antibody detects a CD43 epitope involved in lymphocyte activation:
M. Alvarado, et al.; Eur. J. Immunol.
25
, 1051 (1995)
Abstract
The CBF.78 monoclonal antibody to human sialophorin has distinct properties giving new insights into the CD43 marker and its activation pathway:
J. Tkaczuk, et al.; Tissue Antigens
54
, 1 (1999)
Abstract
Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules:
L. Cermak, et al.; J. Biol. Chem.
277
, 7955 (2002)
Abstract
;
Full Text
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-805-041
Revised 04-Jan-06
Monoclonal Antibody to CD45 (human) (MEM-28)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD45 / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-805-041-C100
100 µg
195.00 USD
ALX-805-041F-T100
FITC
100 tests
270.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
MEM-28
ISOTYPE:
Mouse IgG1
CONCENTRATION:
MEM-28
: 1mg/ml.
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
MEM-28
: Liquid. In PBS, pH 7.4, containing 15mM sodium azide.
MEM-28-FITC
: Liquid. In PBS containing 15mM sodium azide and 0.2% BSA.
IMMUNOGEN:
Human thymocytes and T lymphocytes.
SPECIFICITY:
Recognizes all isoforms of human CD45.
APPLICATION:
MEM-28
:
Flow Cytometry
Immunohistochemistry (paraffin sections - no pre-treatment of tissue sections)
Immunoprecipitation
Western Blot
MEM-28-FITC
:
Flow Cytometry (use 20µl for 100µl of whole blood or 10
6
cells in a suspension)
SHIPPING:
SHIPPED ON BLUE ICE
USE/STABILITY:
MEM-28
: Long Term Storage: -20°C. Avoid freeze/thaw cycles.
MEM-28-FITC
: Long Term Storage: +4°C. Do not freeze. Protect from light.
Product Specific Literature References
Monoclonal antibodies against human leucocyte antigens. I. Antibodies against beta-2-microglobulin, immunoglobulin kappa light chains, HLA-DR-like antigens, T8 antigen, T1 antigen, a monocyte antigen, and a pan-leucocyte antigen:
V. Horejsi, et al.; Folia Biol (Praha)
32
, 12 (1986)
Abstract
Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74):
V. Horejsi, et al.; Folia Biol (Praha)
34
, 23 (1988)
Abstract
Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules:
L. Cermak, et al.; J. Biol. Chem.
277
, 7955 (2002)
Abstract
;
Full Text
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-805-042
Revised 04-Jan-06
Monoclonal Antibody to CD99R (human) (MEM-131)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-805-042-C100
100 µg
210.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
MEM-131
ISOTYPE:
Mouse IgM
FORMULATION:
Contains 0.05% sodium azide.
IMMUNOGEN:
Human T cell line HPB-ALL.
SPECIFICITY:
Recognizes human CD99R.
APPLICATION:
Flow Cytometry
Immunoprecipitation
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
Product Specific Literature References
Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules:
L. Cermak, et al.; J. Biol. Chem.
277
, 7955 (2002)
Abstract
;
Full Text
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-805-043
Revised 18-Mar-08
Monoclonal Antibody to CD18 (human) (MEM-148)
SYNONYMS
anti-β2 Integrin (human) MAb (MEM-148)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD11a, CD18 [LFA-1] & CD54 [ICAM-1], CD102 [ICAM-2], CD50 [ICAM-3] / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-805-043-C100
100 µg
225.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
MEM-148
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE)
PURITY DETAIL:
Protein A-affinity purified.
FORMULATION:
Liquid. In PBS, pH 7.4, containing 15 mM sodium azide.
IMMUNOGEN:
Human peripheral blood mononuclear cells.
SPECIFICITY:
Recognizes free human CD18 (β2 integrin) not associated with CD11. Does not cross-react with pig CD18.
APPLICATION:
Flow Cytometry
Immunoprecipitation
Western Blot (non-reducing)
Functional Application (induces homotypic cell aggregation and high-affinity LFA-1 conformation in resting leukocytes)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Specific Literature References
Human leukocytes contain a large pool of free forms of CD18:
K. Drbal, et al.; BBRC
275
, 295 (2000)
Abstract
A novel anti-CD18 mAb recognizes an activation-related epitope and induces a high-affinity conformation in leukocyte integrins:
K. Drbal, et al.; Immunobiology
203
, 687 (2001)
Abstract
A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells:
K. Drbal, et al.; Blood
98
, 1561 (2001)
Abstract
;
Full Text
Further Categories Containing This Product:
Complement Receptors / Related Products
•
Monoclonal Antibodies
•
CD Antibodies
•
Integrins / Related Products
ALX-805-044
Revised 10-Nov-04
Monoclonal Antibody to CD83 (human) (4B5)
