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Angiopoietin-like Proteins [ANGPTLs]/Related Products
You are here: Product Lines > Obesity & Adipokines > Adipokines/Related Products > Angiopoietin-like Proteins [ANGPTLs]/Related Products
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ALX-201-385 Revised 11-Jun-08
ANGPTL5 (Coiled-coil Domain) (human) (recombinant)
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SYNONYMS Angiopoietin-like Protein 5 (Coiled-coil Domain) (human) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-385-C010   10 µg 310.00 USD Add To Cart
ALX-201-385-C050   50 µg 810.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. Signal peptide and coiled-coil domain of human ANGPTL5 (angiopoietin-like protein 5) (aa 1-130) is fused at the C-terminus to a FLAG®-tag.
CONCENTRATION: 0.5mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
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BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link Q86XS5: Angiopoietin-related protein 5 (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
ALX-201-393 Revised 18-Mar-08
ANGPTL5 (Fibrinogen-like Domain) (human) (recombinant)
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SYNONYMS Angiopoietin-like Protein 5 (Fibrinogen-like Domain) (human) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-393-C010   10 µg 270.00 USD Add To Cart
ALX-201-393-C050   50 µg 780.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. Fibrinogen-like domain of human ANGPTL5 (angiopoietin-like protein 5) (aa 146-388) is fused at the N-terminus to a FLAG®-tag.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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General Information
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link Q86XS5: Angiopoietin-related protein 5 (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
ALX-201-337 Revised 18-Mar-08
ANGPTL6 (human) (recombinant)
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SYNONYMS Angiopoietin-like Protein 6 (human) (recombinant)
AGF (human) (recombinant)
Angiopoietin-related Growth Factor (human) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-337-C010   10 µg 295.00 USD Add To Cart
ALX-201-337-C050   50 µg 795.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. Mature human ANGPTL6 (angiopoietin-like protein 6; AGF) (aa 21-470) is fused at the N-terminus to a FLAG®-tag.
CONCENTRATION: 0.3mg/ml 
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot Link Q8NI99: Angiopoietin-related protein 6 (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
Related Products
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
ALX-201-394 Revised 18-Mar-08
ANGPTL6 (Fibrinogen-like Domain) (human) (recombinant)
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SYNONYMS Angiopoietin-like Protein 6 (Fibrinogen-like Domain) (human) (recombinant)
AGF (Fibrinogen-like Domain) (human) (recombinant)
Angiopoietin-related Growth Factor (Fibrinogen-like Domain) (human) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-394-C010   10 µg 240.00 USD Add To Cart
ALX-201-394-C050   50 µg 710.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. Mature human ANGPTL6 (angiopoietin-like protein 6; AGF) (aa 231-470) is fused at the N-terminus to a FLAG®-tag.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
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General Information
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot Link Q8NI99: Angiopoietin-related protein 6 (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
Related Products
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
ALX-201-368 Revised 04-Apr-07
ANGPTL7 (human) (recombinant)
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SYNONYMS Angiopoietin-like Protein 7 (human) (recombinant)
Cornea-derived Transcript 6 Protein (human) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-368-C010   10 µg 295.00 USD Add To Cart
ALX-201-368-C050   50 µg 795.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. Human ANGPTL7 (angiopoietin-like protein 7) (aa 1-346) is fused at the C-terminus to a FLAG®-tag.
CONCENTRATION:   
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
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General Information
Human ANGPTL7 is produced as a secreted glycoprotein with a molecular mass of 45kDa in SDS-PAGE analysis. Human mRNA is expressed in neural tissues, keratoconus cornea, trabecular meshwork, melanotic melanoma and uterus endometrial cancer, while mouse Angptl7 mRNA is expressed in four-cell embryos, synovial fibroblasts, thymus, uterus and testis. ANGPTL7 reduces tumor growth and aberrant blood vessel formation by inducing massive fibrosis in a mouse xenograft model [1]. It was reported that addition of ANGPTL7 results in a further increase in HSC activities. This suggests that ANGPTL7 may activate signal transduction pathways that cannot be activated by SCF, TPO, IGF-2 or FGF-1 [2]. Human ANGPTL7, characterized as potent target gene of WNT/ beta-catenin signalling pathway, is a pharmacogenomics target in the fields of oncology and regenerative medicine [3].
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link O43827: Angiopoietin-related protein 7 (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
General Literature References
[1] The angiopoietin-like factor cornea-derived transcript 6 is a putative morphogen for human cornea: R. Peek, et al.; J. Biol. Chem. 277, 686 (2002) Abstract; Full Text
[2] Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells: C.C. Zhang, et al.; Nat. Med. 12, 240 (2006) Abstract
[3] Comparative integromics on Angiopoietin family members: Y. Katoh and M. Katoh; Int. J. Mol. Med. 17, 1145 (2006) Abstract
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
ALX-201-395 Revised 18-Mar-08
ANGPTL7 (Fibrinogen-like Domain) (human) (recombinant)
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SYNONYMS Angiopoietin-like Protein 7 (Fibrinogen-like Domain) (human) (recombinant)
Cornea-derived Transcript 6 Protein (Fibrinogen-like Domain) (human) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-395-C010   10 µg 250.00 USD Add To Cart
ALX-201-395-C050   50 µg 560.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. Mature human ANGPTL7 (angiopoietin-like protein 7) (aa 126-346) is fused at the N-terminus to a FLAG®-tag.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot Link O43827: Angiopoietin-related protein 7 (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
ALX-804-635 Revised 18-Jan-07
Monoclonal Antibody to ANGPTL3 (human) (1D10)
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SYNONYMS anti-Angiopoietin-like Protein 3 (human) MAb (1D10)
anti-Angiopoietin-5 (human) MAb (1D10)
anti-ANG-5 (human) MAb (1D10)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-635-R050   50 µl 195.00 USD Add To Cart
ALX-804-635-R100   100 µl 320.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 1D10
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS, pH 7.4, containing 0.02% thimerosal.
IMMUNOGEN: Recombinant human ANGPTL3 (angiopoietin-like protein 3) (aa 243-460).
SPECIFICITY: Recognizes human ANGPTL3. Detects bands of ~64kDa (full-length) and ~36kDa (cleaved ANGPTL3) by Western blot.
APPLICATION: ELISA
Western Blot (1:500-1:2’000)
Recommended starting dilution is 1:1’000.
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
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Product Specific Literature References
[1] Angiopoietin-like protein 3 mediates hypertriglyceridemia induced by the liver X receptor: T. Inaba, et al.; J. Biol. Chem. 278, 21344 (2003) Abstract; Full Text
[2] Protein region important for regulation of lipid metabolism in angiopoietin-like 3 (ANGPTL3): ANGPTL3 is cleaved and activated in vivo: M. Ono, et al.; J. Biol. Chem. 278, 41804 (2003) Abstract; Full Text
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Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-724 Revised 15-May-08
Monoclonal Antibody to ANGPTL3 (human) (Kairos-37)
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SYNONYMS anti-Angiopoietin-like Protein 3 (human) MAb (Kairos-37)
anti-Angiopoietin-5 (human) MAb (Kairos-37)
anti-ANG-5 (human) MAb (Kairos-37)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-724-C050   50 µg 195.00 USD Add To Cart
ALX-804-724-C100   100 µg 270.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: Kairos-37
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human ANGPTL3 (angiopoietin-like protein 3; ANG-5).
SPECIFICITY: Recognizes the fibrinogen-like domain (FLD) of human ANGPTL3. Detects a band of ~68kDa and a cleaved band of ~35kDa by Western blot. Does not cross-react with other ANGPTL family proteins.
APPLICATION: ELISA (direct and indirect: 1:1’000-1:5’000)
Western Blot (1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
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General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Related Products
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-731 Revised 02-Jul-08
Monoclonal Antibody to ANGPTL4 (Coiled-coil Domain) (human) (Kairos4-153AD)
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SYNONYMS anti-Angiopoietin-like Protein 4 (Coiled-coil Domain) (human) MAb (Kairos4-153AD)
anti-FIAF (Coiled-coil Domain) (human) MAb (Kairos4-153AD)
anti-Fasting-induced Adipose Factor (Coiled-coil Domain) (human) MAb (Kairos4-153AD)
anti-HFARP (Coiled-coil Domain) (human) MAb (Kairos4-153AD)
anti-Hepatic Fibrinogen/Angiopoietin-related Protein (Coiled-coil Domain) (human) MAb
(Kairos4-153AD)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart