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Interleukins & Interleukin Receptors / Related Products
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ALX-210-447 Revised 07-Oct-08
Polyclonal Antibody to IL-33 (human)
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SYNONYMS anti-Interleukin-33 (human) PAb
anti-NF-HEV (human)
anti-IL-1F11 (human) PAb
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Antibodies
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-447-C100   100 µg 310.00 USD Add To Cart
ALX-210-447B-C050 Biotin 50 µg 310.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Purified IgG.
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human IL-33 (interleukin-33).
SPECIFICITY: Recognizes human IL-33.
APPLICATION: ELISA (direct and indirect: 1:2’000-1:5’000)
Western Blot (1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for 6 months after receipt when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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Product Specific Literature References
IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo: V. Carriere et al.; PNAS 104, 282 (2007) Abstract
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Interleukin-33 [IL-33] & Receptors / Related ProductsPolyclonal Antibodies
 
 
ALX-210-449 Revised 07-Oct-08
Polyclonal Antibody to IL-33 (mouse)
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SYNONYMS anti-Interleukin-33 (mouse) PAb
anti-NF-HEV (mouse)
anti-IL-1F11 (mouse) PAb
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Antibodies
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-449-C100   100 µg 310.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Purified IgG.
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant mouse IL-33 (interleukin-33).
SPECIFICITY: Recognizes mouse IL-33. Does not cross-react with human IL-33.
APPLICATION: ELISA (direct and indirect: 1:2’000-1:5’000)
Western Blot (1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for 6 months after receipt when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Interleukin-33 [IL-33] & Receptors / Related ProductsPolyclonal Antibodies
 
 
ALX-210-459 Revised 02-Aug-07
Polyclonal Antibody to IL-23p19
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SYNONYMS anti-Interleukin-23p19 PAb
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Antibodies
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-459-C100   100 µg 310.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Purified IgG.
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant mouse IL-23p19 (interleukin-23p19).
SPECIFICITY: Recognizes mouse IL-23p19. Cross-reacts with human IL-23p19:Fc and human single chain IL-23.
APPLICATION: ELISA (direct and indirect: 1:2’000-1:10’000)
Western Blot (1:2’000-1:10’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for 1-2 weeks when stored at +4°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-461 Revised 07-Oct-08
Polyclonal Antibody to ST2 (human)
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SYNONYMS anti-IL-1 Receptor-like 1 (human) PAb
anti-Interleukin-1 Receptor-like 1 (human) PAb
anti-IL1RL1 (human) PAb
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Receptors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-461-C100   100 µg 310.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Purified IgG.
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human ST2.
SPECIFICITY: Recognizes human ST2.
APPLICATION: ELISA (direct and indirect: 1:2’000-1:5’000)
Western Blot (1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for 1-2 weeks when stored at +4°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Interleukin-33 [IL-33] & Receptors / Related ProductsPolyclonal Antibodies
 
 
ALX-201-370 Revised 07-Oct-08
ST2 (human) (recombinant)
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SYNONYMS IL-1 Receptor-like 1 (human) (recombinant)
Interleukin-1 Receptor-like 1 (human) (recombinant)
IL1RL1 (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Receptors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-370-C050   50 µg 795.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. The signal peptide and the sequence of isoform 2 of human ST2 (IL1RL1) (aa 1-328) are fused at the C-terminus to a FLAG®-tag.
CONCENTRATION: 0.5mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS, pH 7.2.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles.
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General Information
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link Q01638: Interleukin-1 receptor-like 1 (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.

MANUFACTURER Manufactured by AdipoGen, Inc.
 
 
ALX-201-367 Revised 07-Oct-08
ST2 (human):Fc (human) (recombinant)
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SYNONYMS IL-1 Receptor-like 1 (human):Fc (human) (recombinant)
Interleukin-1 Receptor-like 1 (human):Fc (human) (recombinant)
IL1RL1 (human):Fc (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Receptors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-367-C050   50 µg 410.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. The signal peptide and the sequence of isoform 2 of human ST2 (IL1RL1) (aa 1-328) are fused at the C-terminus to the Fc portion of human IgG1.
CONCENTRATION: 0.25mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS, pH 7.2.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
BIOLOGICAL ACTIVITY: Interacts with human IL-33 as confirmed by pull-down assay (see figure 2).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap. After opening, prepare aliquots and store at -20°C.
Product Images
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General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q01638: Interleukin-1 receptor-like 1 (human) [Precursor]
MANUFACTURER Manufactured by AdipoGen, Inc.
 
 
ALX-522-107 Revised 07-Oct-08
ST2 (mouse):Fc (human) (recombinant)
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SYNONYMS IL-1 Receptor-like 1 (mouse):Fc (human) (recombinant)
Interleukin-1 Receptor-like 1 (mouse):Fc (human) (recombinant)
IL1RL1 (mouse):Fc (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Interleukin Receptors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-522-107-C050   50 µg 350.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST: Produced in CHO cells. Mouse ST2 (aa 27-332) is fused to the Fc portion of human IgG1.
CONCENTRATION: 1mg/ml after reconstitution.
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Lyophilized. Contains PBS.
ENDOTOXIN CONTENT: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION: Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
SPECIFICITY: Binds to mouse and human IL-33.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -20°C.
HANDLING: After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
General Information
ST2 is a transmembrane receptor of the new IL-1 family member IL-33. It induces the NF-κB pathway upon its activation and is involved in T helper type 2 response driving the production of Th2-associated cytokines. ST2 is predominantly expressed in hematopoietic tissues, and in macrophage, erythroid, epithelial and fibroblast cell lines.
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link P14719: Interleukin-1 Receptor-like 1 (mouse)

MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines: J. Schmitz, et al.; Immunity 23, 479 (2005) Abstract
 
 

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