Advanced Search
© 2008 Alexis Corporation
You are here:
Product Lines
> Chemokines & Cytokines
Adipokines / Related Products
Chemokines & Chemokine Receptors / Related Products
Growth Factors / Related Products
Interferons & Interferon Receptors / Related Products
Interleukins & Interleukin Receptors / Related Products
Stem Cell and Differentiation Factors / Related Products
TNF & TNF Receptor Superfamily / Related Products
Chemokines & Cytokines Other Products
Toolbar - View Selection
Current View:
Price List
Brief
Detail
Search Results
Current Sort:
Sort by Product Name
Sort by Product ID
Sort by Result Relevance
Sort by Class
Show:
20 Products
50 Products
100 Products
All Products
Show Selected Products Only
Show
Products Only
Items
300-400
of 690
Page 4
of 7
Select Page:
<<
1
2
3
4
5
6
7
>>
ALX-804-518
Revised 31-Oct-06
Monoclonal Antibody to GITRL (mouse) (MGTL 10)
SYNONYMS
anti-TNFSF 18 (mouse) MAb (MGTL 10)
anti-Glucocorticoid-induced TNF Receptor Ligand (mouse) MAb (MGTL 10)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
GITR & GITRL Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-518-C050
50 µg
220.00 USD
ALX-804-518-C100
100 µg
290.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE:
MGTL 10
ISOTYPE:
Rat IgG2a
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Recombinant mouse GITRL.
SPECIFICITY:
Recognizes both natural and recombinant mouse GITRL. Does not cross-react with human GITRL (AITRL).
APPLICATION:
ELISA
(direct and indirect: 1:5’000-1:10’000)
Flow Cytometry (excellent)
(1:1’000)
Western Blot
(1:2’000-1:5’000 using ECL; suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk; incubate 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-kappaB ligand (RANKL) in osteoclast cells:
H.H. Shin, et al.; Bone
36
, 832 (2005)
Abstract
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-519
Revised 27-Feb-08
Monoclonal Antibody to GITRL (mouse) (MGTL 15)
SYNONYMS
anti-TNFSF 18 (mouse) MAb (MGTL 15)
anti-Glucocorticoid-induced TNF Receptor Ligand (mouse) MAb (MGTL 15)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
GITR & GITRL Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-519-C050
50 µg
220.00 USD
ALX-804-519-C100
100 µg
290.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE:
MGTL 15
ISOTYPE:
Rat IgG2a
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Recombinant mouse GITRL.
SPECIFICITY:
Recognizes both natural and recombinant mouse GITRL. Does not cross-react with human GITRL (AITRL).
APPLICATION:
ELISA
(direct and indirect: 1:5’000-1:10’000)
Flow Cytometry
(1:1’000)
Western Blot (excellent)
(1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-339
Revised 14-Nov-08
Monoclonal Antibody to GM-CSF (mouse) (MP1-22E9)
SYNONYMS
anti-Granulocyte-macrophage Colony Stimulating Factor (mouse) MAb (MP1-22E9)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
Granulocyte-Macrophage Colony-Stimulating Factor [GM-CSF] / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-339-C100
100 µg
259.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE:
MP1-22E9
ISOTYPE:
Rat IgG2a
CONCENTRATION:
0.5mg/ml.
FORMULATION:
Liquid. Antibody in PBS, pH 7.4, containing 0.1% sodium azide.
IMMUNOGEN:
Mouse GM-CSF (granulocyte-macrophage colony stimulating factor).
SPECIFICITY:
Recognizes mouse GM-CSF.
APPLICATION:
ELISA
Immunohistochemistry
(frozen sections)
Western Blot
(1-5µg/ml detects less than 100ng protein under reducing conditions)
Functional Application
(neutralizing)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Specific Literature References
Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining:
B. Sander, et al.; J. Immunol. Methods
166
, 201 (1993)
Abstract
Early expression of cytokines in lymph nodes after treatment in vivo with Staphylococcus enterotoxin B:
M.J. Litton, et al.; J. Immunol. Methods
175
, 47 (1994)
Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-382
Revised 21-Feb-08
Monoclonal Antibody to Hrs and Hrs-2 (A-5)
SYNONYMS
anti-HGS MAb (A-5)
anti-Hepatocyte Growth Factor-regulated Tyrosine Kinase Substrate MAb (A-5)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
Hepatocyte Growth Factor [HGF] & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-382-C050
50 µg
290.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Monkey
CLONE:
A-5
ISOTYPE:
Mouse IgG2a
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. In PBS containing 1
0% glycerol.
IMMUNOGEN:
Recombinant full length rat Hrs-2 (hepatocyte growth factor-regulated tyrosine kinase substrate).
SPECIFICITY:
Recognizes human, mouse, rat and monkey Hrs (HGS) and Hrs-2.
APPLICATION:
Immunohistochemistry (1:100-1:1'000)
Immunoprecipitation (2µg/ml)
Western Blot (1:2'000-1:3'000)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for 3 months when stored at +4°C.
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
Isoform-specific exocytotic protein mRNA expression in hypothalamic magnocellular neurons: regulation after osmotic challenge
:
G. Jacobsson, et al.; Neuroendocrinology
70
, 392 (1999)
Abstract
The cellular and developmental expression of hrs-2 in rat
:
S. Tsujimoto, et al.; Eur. J. Neurosci.
11
, 3047 (1999)
Abstract
Hrs-2 regulates receptor-mediated endocytosis via interactions with Eps15
:
A.J. Bean, et al.; J. Biol. Chem.
275
, 15271 (2000)
Abstract
;
Full Text
Distinct protein domains are responsible for the interaction of Hrs-2 with SNAP-25. The role of Hrs-2 in 7 S complex formation
:
S. Tsujimoto & A.J. Bean; J. Biol. Chem.
275
, 2938 (2000)
Abstract
;
Full Text
SNAP-25-associated Hrs-2 protein colocalizes with AQP2 in rat kidney collecting duct principal cells:
A. Shukla, et al.; Am. J. Physiol. Renal. Physiol.
281
, F546 (2001)
Abstract
;
Full Text
CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling:
Q. Yan, et al.; Mol. Biol. Cell
16
, 2470 (2005)
Abstract
;
Full Text
Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) interacts with PELP1 and activates MAPK:
S.K. Rayala, et al.; J. Biol. Chem.
281
, 4395 (2006)
Abstract
;
Full Text
General Information
Hrs/Hgs (hepatocyte growth factor-regulated tyrosine kinase substrate) is a tyrosine-phosphorylated member of a protein family characterized by a conserved 3´-phosphoinositide-interacting RING zinc finger domain, the so called FYVE finger. A variant of Hrs, Hrs-2 is an ATPase that has been shown to play a regulatory role in the docking and/or fusion of synaptic vesicles to plasma membranes through a calcium-regulated interaction with SNAP-25. Hrs-2 physically interacts with Eps15, a protein required for receptor-mediated endocytosis. The Hrs-2/Eps15 interaction is calcium dependent, inhibited by SNAP-25 and alpha-adaptin, and results in the inhibition of receptor-mediated endocytosis. Immunoelectron microscopy reveals Hrs-2 localization on the limiting membrane of multivesicular bodies, organelles in the endosomal pathway. Recent data suggest that Hrs-2 acts to provide communication between endo- and exocytic processes.
Further Categories Containing This Product:
Vesicles & Membrane Trafficking Other Products
•
Monoclonal Antibodies
•
Autophagy-related Proteins [APG; ATG] / Related Products
ALX-804-814
Revised 26-Feb-07
Monoclonal Antibody to HVEM (human) (Laury-1)
SYNONYMS
anti-Herpesvirus Entry Mediator A (human) MAb (Laury-1)
anti-ATAR (human) MAb (Laury-1)
anti-LIGHT-R (human) MAb (Laury-1)
anti-TR2 (human) MAb (Laury-1)
anti-TNFRSF 14 (human) MAb (Laury-1)
anti-Tumor Necrosis Factor Receptor-like 2 (human) MAb (Laury-1)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
HVEM & LIGHT / LT-betaR / DcR3 / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-814-C100
100 µg
320.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
Laury-1
ISOTYPE:
Rat IgG2a
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE)
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Recombinant human HVEM extracellular domain (aa 39-200) (Prod. No.
ALX-522-017
).
SPECIFICITY:
Recognizes human HVEM.
APPLICATION:
Flow Cytometry (1:1'000)
Immunoprecipitation (1:200)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:
Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
General Literature References
Tumor necrosis factor receptor and Fas signaling mechanisms
:
D. Wallach, et al.; Annu. Rev. Immunol.
17
, 331 (1999), (Review)
Abstract
Involvement of tumor necrosis factor receptor superfamily(TNFRSF) members in the pathogenesis of inflammatory diseases
:
B. Kwon, et al.; Exp. Mol. Med.
35
, 8 (2003), (Review)
Abstract
;
Full Text
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-461
Revised 01-Oct-08
Monoclonal Antibody to IL-1 Receptor Type II (human) (MNC2)
SYNONYMS
anti-IL-1RII (human) MAb (MNC2)
anti-CD121b (human) MAb (MNC2)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
Interleukin Receptor Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-461-C100
100 µg
350.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
MNC2
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. Purified antibody in PBS containing 0.1% sodium azide.
IMMUNOGEN:
Recombinant human IL-1RII (interleukin-1 receptor type II; CD121b).
SPECIFICITY:
Recognizes human IL-1RII.
APPLICATION:
ELISA (capture)
Flow Cytometry (excellent)
Immunohistochemistry
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Interleukin-1 [IL-1] & Receptors / Related Products
•
Monoclonal Antibodies
•
CD Antibodies
ALX-804-338
Revised 28-Nov-07
Monoclonal Antibody to IL-1F1 (mouse) (Flo1)
SYNONYMS
anti-Interleukin-1 Family Member 1 (mouse) MAb (Flo1)
anti-IL-1α (mouse) MAb (Flo1)
anti-Interleukin-1α (mouse) MAb (Flo1)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
Interleukin Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-338-C100
100 µg
259.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE:
Flo1
ISOTYPE:
Mouse IgG1
IMMUNOGEN:
Mouse IL-1F1 (IL-1α).
SPECIFICITY:
Recognizes mouse IL-1F1.
APPLICATION:
ELISA
Functional Application (neutralizing)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
Product Specific Literature References
Functional discrimination between interleukin 6 and interleukin 1:
M. Helle, et al.; Eur. J. Immunol.
18
, 1535 (1988)
Abstract
Further Categories Containing This Product:
Interleukin-1 [IL-1] & Receptors / Related Products
•
Monoclonal Antibodies
ALX-804-462
Revised 02-Mar-06
Monoclonal Antibody to IL-1ra3 (human) (MND1)
SYNONYMS
anti-icIL-1raII (human) MAb (MND1)
anti-IL-1 Receptor Agonist Type II (intracellular isoform) (human) MAb (MND1)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
Interleukin & Interleukin Receptors Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-462-C100
100 µg
350.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
MND1
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. Purified antibody in PBS containing 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to a partial sequence (ADLYEEGGGGGGEGEDNADSK) of human IL-1ra3.
SPECIFICITY:
Recognizes human IL-1ra3.
APPLICATION:
Immunohistochemistry
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
Characterization of type II intracellular IL-1 receptor antagonist (IL-1ra3): a depot IL-1ra
:
M. Muzio, et al.; Eur. J. Immunol.
29
, 781 (1999)
Abstract
Further Categories Containing This Product:
Interleukin-1 [IL-1] & Receptors / Related Products
•
Monoclonal Antibodies
ALX-804-337
Revised 30-Aug-07
Monoclonal Antibody to IL-2 (mouse) (JES6-5H4)
SYNONYMS
anti-Interleukin-2 (mouse) MAb (JES6-5H4)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
Interleukin Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-337-C100
100 µg
259.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE:
JES6-5H4
ISOTYPE:
Rat IgG2b
CONCENTRATION:
0.5mg/ml
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
Liquid. In PBS, pH 7.4 containing 0.1% sodium azide.
IMMUNOGEN:
Recombinant mouse IL-2 (interleukin-2).
SPECIFICITY:
Recognizes mouse IL-2.
APPLICATION:
ELISA
Flow Cytometry
Immunohistochemistry (frozen sections)
Immunoprecipitation
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Specific Literature References
Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples:
J.S. Abrams, et al.; Immunol. Rev.
127
, 5 (1992)
Abstract
Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining:
B. Sander, et al.; J. Immunol. Methods
166
, 201 (1993)
Abstract
Increase in orthotopic murine corneal transplantation rejection rate with anterior synechiae
:
S. Yamagami & T. Tsuru; Invest. Ophthalmol. Vis. Sci.
40
, 2422 (1999)
Abstract
;
Full Text
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-726
Revised 02-Oct-08
Monoclonal Antibody to IL-33 (human) (IL33305B)
SYNONYMS
anti-Interleukin-33 (human) MAb (IL33305B)
anti-NF-HEV (human) MAb (IL33305B)
anti-IL-1F11 (human) MAb (IL333305B)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
Interleukin Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-726-C050
50 µg
195.00 USD
ALX-804-726-C100
100 µg
360.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
IL33305B
ISOTYPE:
Mouse IgG2a
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Recombinant human IL-33 (interleukin-33).
SPECIFICITY:
Recognizes human IL-33. Does not cross-react with mouse IL-33.
APPLICATION:
ELISA
(direct and indirect: 1:2’000-1:5’000)
Western Blot
(1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Immunoprecipitation
Functional Application
(Neutralization)
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for 1-2 weeks when stored at +4°C.
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
